central nervous disease
Conditions
Interventions
Cognitive stimulation therapy
50 participants over 60 years of age diagnosed with dementia will be randomized into two groups. Intervention group: 25 elderly people with dementia will be distributed i
Control group: 25 elderly people with dementia will receive the usual treatment, which is the recommended drug treatment for dementia and Regular medical visits at the discretion of the attending phys
Other
Sponsors
Pontifícia Universidade Católica do Rio de Janeiro
Pontifícia Universidade Católica do Rio de Janeiro
Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro
Eligibility
Age
60 Years to 95 Years
Inclusion criteria
Inclusion criteria: Age over 60 years; Both genders; People diagnosed with dementia; Score between 10 and 24 on the Mini Mental State Exam; Be able to answer neuropsychological evaluation.
Exclusion criteria
Exclusion criteria: Age greater than 95 years. Mental retardation previously diagnosed according to ICD criteria 10.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is enhancement in cognition, as measured by the Cognitive Alzheimer's Disease Assessment (ADAS-Cog) scale. ADAS-Cog uses 11 tasks to measure cognitive domains, such as memory, praxis, and language. The differences in the responses found in the scales applied at the beginning and at the end of the study will be evaluated through statistical analysis using 2X2 ANOVA. Considering that this is a validation study, the analyzes will be exploratory. The scales will be applied within two weeks before the start of the study and within one week after the end of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include imporbvement in quality of life as measured by QoL-AD scale, imporvement in depressive symptoms as measured by Cornell Scale for Depression in Dementia (CSDD), imporvement in disease awareness as measured by ASPIDD scale and reduction in caregiver bruden as measured by Zarit Burden Scale (ZBI). The differences in the responses found in the scales applied at the beginning and at the end of the study will be evaluated. The scales will be applied within two weeks before the start of the study and within one week after the end of the study. | — |
Countries
Brazil
Contacts
Public ContactDaniel Mograbi
Pontifícia Universidade Católica do Rio de Janeiro
Outcome results
None listed