Ophthalmopathies, mydriasis, vitrectomy, epinephrine, pupil disorders
Conditions
Interventions
Experimental group: 45 patients with pars plana vitrectomy indication with pupils previously dilated with 3 tropicamide consecutive drops, will have the pupillary diameter measured with a millimeter s
Procedure/surgery
E04.540.960
C10.597.690
D02.033.100.291.310
Sponsors
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - HCFMUSP
Hospital Universitário Onofre Lopes da Universidade Federal do Rio Grande do Norte - HUOL/UFRN
Eligibility
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients submitted to isolated vitrectomy; Age of 18 or higher.
Exclusion criteria
Exclusion criteria: Pseudophakic patients with the cataract surgery performed in less than 6 months; History of uveitis; pseudoexfoliation; trauma; use of any systemic or topical anti-inflammatory medications within 2 weeks to surgery; Intraoperative complications; Patients submitted to scleral buckling or any anterior chamber procedure during vitrectomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected endpoint: Mean difference between pupil diameter measured at the end of the surgery of at least 1 mm larger in group epinephrine than placebo.;Endpoint found: Mean difference between pupil diameter measured at the end of the surgery of 1.1 mm larger in group epinephrine than placebo. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected endpoint: Difference of at least 1 mm between the end of surgery and before surgery pupillary diameter measurements.;Endpoint found: Difference of 0.6 and -0.3 mm between the end of surgery and before surgery pupillary diameter measurements in the experimental and control group, respectively. | — |
Countries
Brazil
Contacts
Public ContactRafael de Araujo
Hospital Universitário Onofre Lopes da Universidade Federal do Rio Grande do Norte - HUOL/UFRN
Outcome results
None listed