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Effect of aqueous propolis extract on gingival tissue healing

Evaluation of the effect of aqueous propolis extract on gingival tissue healing in smile correction surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3qpyh3y
Enrollment
Unknown
Registered
2022-02-15
Start date
2021-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Participants must present clinical indications that indicate the performance of smile correction surgery, which would be showing more than 2 mm of gingiva when smiling, having a short clinical crown and longer anatomical crown and/or altered passive eruption. Descriptors: Gingivia

Interventions

All surgical procedures will be performed by the same operator in a standardized way. Before surgery, the patient will have a mouth rinse with 0.12% chlorhexidine solution (intra-oral antisepsis) and
DFL, Rio de Janeiro, RJ, Brazil), an incision will be made in an internal bevel 1 to 3 mm apical to the gingival margin, followed by an intra-sulcular incision with a blade scalpel 15C (Swann-Morton,
2) Test group – Mouthwash with aqueous extract of propolis twice a day (12 every 12 hours), for 15 days + 6 tablets of Paracetamol 750 mg 8/8 hours for 2 days in case of pain.
D011429
D014945

Sponsors

Jéssica Gomes Alcoforado de Melo
Lead Sponsor
Jéssica Gomes Alcoforado de Melo
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: -Have another two millimeters of gingiva band visible to the smile. -Show gum health. -Have an indication to perform a smile correction in the upper arch of at least canine to canine (from teeth 13, 12, 11, 21, 22 and 23). -Be healthy systemically. -Agree to participate in the research by signing the Informed Consent Form and having received, verbally and in writing by the researchers, all information and clarifications.

Exclusion criteria

Exclusion criteria: Those who, even if they present indications for correction of the smile, need some postoperative rehabilitation procedure, due to the small size of the anatomical crown, and those who are allergic to any of the drugs used in the study (chlorhexidine, aqueous extract of propolis, will be excluded from the sample). , paracetamol, 2% mepivacaine with epinephrine 1:100,000).

Design outcomes

Primary

MeasureTime frame
It is expected to prove that the propolis aqueous extract mouthwash has good action in the healing process of gingival tissues, that it presents an antiplaque effect compatible with 0.12% chlorhexidine and that the topical use of propolis positively influences in the reduction of postoperative pain in gummy smile correction surgeries. As well as proving that low-power laser therapy has a beneficial effect on healing and postoperative pain control in patients undergoing surgery to correct gummy smile.

Secondary

MeasureTime frame
Postoperative pain control by using propolis.

Countries

Brazil

Contacts

Public ContactJéssica Melo

Faculdade de Integração do Sertão

gameloj@gmail.com+55(81)99816-9443

Outcome results

None listed

Source: REBEC (via WHO ICTRP)