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Weight Training, Apathy and Motor Function in Alzheimer's Disease

Weight Training, Apathy Syndrome and Motor Function in Patients With Alzheimer's Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3q3q98
Enrollment
Unknown
Registered
2013-02-22
Start date
2011-03-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer´s disease, Apathy, Reduced motor function

Interventions

The training group consisted of 14 patients will perform weight training for four months, on nonconsecutive days, 60 minutes each session. Will be performed three sets of 20 repetitions for the major
other

Sponsors

Universidade Estadual Paulista Júlio de Mesquita Filho
Lead Sponsor
Universidade Estadual Paulista Júlio de Mesquita Filho
Collaborator
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Collaborator

Eligibility

Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients diagnosed with Alzheimer´s disease both genders aged 60 years and over. Elderly people with mild and moderate levels of dementia. Patients and their caregivers that were consistent with the procedures of the study and who signed the Instrument of Consent. Patients ambulating

Exclusion criteria

Exclusion criteria: Patients with other neuropsychiatric conditions or clinical comorbidities that interfere with the apathetic condition, provided in front or cognitive motor procedures to be developed. Patients who had contraindications to physical activity. Patients with bone-mioarticulares problems, serious heart disease or amputations

Design outcomes

Primary

MeasureTime frame
Apathy Syndrome - Lowering scores measured using the Neuropsychiatric Inventory (apathy domain) after 4 months of weight training and after 4 months of social interaction in relation to the time prior to this practices;Motor function - After 4 months of weight training and after 4 months of social interaction: Decrease time spent, in seconds, to perform the tests walk 800 meters, to sit and get up from the chair and moving around the house, climbing stairs, getting up from the ground; manuals abilities and put on socks (assessed by Andreotti & Okuma Battery). Moreover, increase in centimeters, the distance reached by the of Wells protocol used to measure flexibility, increase the number of repetitions performed for elbow flexion used to measure the strength of the upper limb (taken from the American Alliance for Health Physical Education Recreation and Dance battery) and increase the number of repetitions performed to sit and get up from the chair used to measure the strength of the lower limbs (removed battery testing Rikli & Jones). Compared to aterior practice of weight training and social interaction;Frontal cognitive functions - Increasing scores measured by the Mini Mental State Examination; Montreal Cognitive Assessment (consists in a scale with nine subtests that assess specific cognitive functions such as abstraction, naming, calculation and others), clock drawing test and frontal assessment battery. Furthermore, increasing the number of words spoken obtained by verbal fluency test after 4 months of weight training and after 4 months of social interaction in relation to the time prior to this practices;Conclusions - After 4 months of weight training there was a significant increase in the number of repetitions performed for elbow flexion test used to measure the strength of the upper limb ( American Alliance for Health Physical Education Recreation and Dance battery tests). There was also a significant increase in the distance, in centimeters, obtained by

Secondary

MeasureTime frame
Depressive symptoms - no more than 7 points score on the Cornell Scale for Depression in Dementia after 4 months of weight training and after 4 month of social interaction;Conclusions - After 4 months of weight training and after 4 months of social interaction patients with Alzheimer's dementia not exceed 7 points on the Cornell Scale for Depression in Dementia

Countries

Brazil

Contacts

Public ContactVagner Morae

Universidade Estadual Paulista Júlio de Mesquita Filho

scaib@rc.unesp.br+55(19)3526-4107

Outcome results

None listed

Source: REBEC (via WHO ICTRP)