Skip to content

prospective randomized study in the use of pregabalin for control and prevention of chronic pain after inguinal hernioplasty

prospective randomized study in the use of pregabalin for control and prevention of chronic pain after inguinal hernioplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-3pgyyq
Enrollment
Unknown
Registered
2019-04-22
Start date
2019-04-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inguinal hernia, pos operatory pain

Interventions

Prospective, randomized, double blind study, admitting 60 patients randomly distributed in 3 groups of 20 patients each. Group A patients (n = 20) will receive pregabalin 300mg, 1 hour before surgery
Drug

Sponsors

universidade de santo amaro
Lead Sponsor
Hospital Geral do Grajaú
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Male patients, aged between 18 and 60 years, with primary unilateral inguinal hernia, without comorbidities

Exclusion criteria

Exclusion criteria: Patients on non-hormonal anti-inflammatory or corticosteroid use prior to surgery, discontinuation of medication use

Design outcomes

Primary

MeasureTime frame
To evaluate if pregabalin reduces the occurrence of chronic postoperative pain, through the method of 2 distinct dosing schedules, compared with placebo. We will observe if there is a decrease in chronic pain varying by at least 5% of the occurrence of chronic pain postoperatively.

Secondary

MeasureTime frame
We'll observate if improvement of the quality of life of patients occure.

Countries

Brazil

Contacts

Public Contactsilvio gabor

universidade de santo amaro

silvio@gabor.com.br+55-11-981117685

Outcome results

None listed

Source: REBEC (via WHO ICTRP)