Influence of changes in the genetics of the hunger hormone called ghrelin and the number of meals per day on weight loss, ghrelin in the blood, intestinal flora and body health indicators in women with obesity

Influence of the Ghrelin Gene Polymorphism and meal frequency on body weight loss, ghrelin levels, gut microbiota and metabolic indicators in women with Obesity

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

REBEC

Registry ID

RBR-3p8346g

Enrollment

Unknown

Registered

2021-06-01

Start date

2021-11-25

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body Weight

Interventions

Experimental group: 100 women with obesity will receive an individualized low-calorie diet to reduce body weight with different numbers of meals per day. Women will be randomized into two groups. Grou

E02.642.249.200

Eligibility

Sex/Gender

Female

Age

25 Years to 45 Years

Inclusion criteria

Inclusion criteria: Adults with obesity; any race or color; nonmenopausal; no change in body weight recently; did not perform bariatric surgery.

Exclusion criteria

Exclusion criteria: Use of medication or supplements for weight control that alter the intestinal microbiota; smokers; drinkers; with complications; cardiac; respiratory; diabetes mellitus; decompensated hypothyroidism; cancer; pregnant women; lactating; illiterate.

Design outcomes

Primary

Measure	Time frame
Obesity that will be identified with the value of the body mass index when the value is greater than or equal to 30 kg / m2	—

Secondary

Measure	Time frame
Secondary outcomes are not expected	—

Countries

Brazil

Contacts

Public ContactErika Grangeiro

erikawduartegs@gmail.com+5521972160611

Outcome results

None listed

Source: REBEC (via WHO ICTRP)