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Reproducibility of blood pressure reduction and its physiological regulators after a sessions of exercise executed in different days

Reproducibility of post-exercise hypotension and its hemodynamic and autonomic mechanisms

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3nxn34
Enrollment
Unknown
Registered
2016-12-29
Start date
2015-08-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normotension, Hypertension

Interventions

A single group of 30 subjects will undergo 4 experimental sessions (crossover study), divided into 2 blocks (test and retest). Each block will be composed by 1 exercise session and 1 control session,
Other
G11.427.590.530.698.277

Sponsors

Escola de Educação Física e Esporte da Universidade de São Paulo
Lead Sponsor
Escola de Educação Física e Esporte da Universidade de São Paulo
Collaborator

Eligibility

Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Both genders Age between 20 and 60 years Blood pressure levels below 160/105 mmHg Absence of cardiovascular disease No use of medications that block the autonomic nervous system Absence of orthopedic problems that contraindicates physical exercise

Exclusion criteria

Exclusion criteria: Presence of complex arrhythmias and/or ischemia during a cardiopulmonary exercise test

Design outcomes

Primary

MeasureTime frame
Good reproducibility of blood pressure reduction after exercise, evaluated by blood pressure measurements, before and after interventions. A good reproducibility will be defined by the following parameters: Absence of systematic error, evaluated by paired t test between test and retest, adopting a significance level of p < 0,05; Good reliability determined by an intraclass correlation coefficient equal or greater than 0,75; Good agreement represented by a low coefficient of variation (<10%).

Secondary

MeasureTime frame
Good reproducibility of cardiac output, heart rate, autonomic cardiac modulation and vascular function, evaluated respectively by CO2 rebreathing, electrocardiogram, spectral analysis of heart rate variability and venous occlusion plethysmography, before and after interventions. A good reproducibility will be defined by the following parameters: Absence of systematic error, evaluated by paired t test between test and retest, adopting a significance level of p < 0,05; Good reliability determined by an intraclass correlation coefficient equal or greater than 0,75; Good agreement represented by a low coefficient of variation (<10%).

Countries

Brazil

Contacts

Public ContactClaudia Forjaz

Escola de Educação Física e Esporte da Universidade de São Paulo

cforjaz@usp.br+55(11)3091-3136

Outcome results

None listed

Source: REBEC (via WHO ICTRP)