Snake Bites
Conditions
Interventions
This is a randomized, controlled, double-blind, two-arm clinical trial. The population considered for this study corresponds to patients treated at the Dr. Heitor Vieira Dourado Tropical Medicine Foun
E02.594
Sponsors
Escola Superior de Ciências da Saúde da Universidade do Estado do Amazonas
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Eligibility
Inclusion criteria
Inclusion criteria: Present clinical characteristics of a Bothrops snakebite accident, regardless of sex and age; have occurred less than 24 hours before the snakebite accident; have not undergone serum therapy for a current Bothrops snakebite accident in another institution; no minimum age was defined, however, in relation to children, only those who understand the procedure, agree to participate in the research together with their legal guardian and who understand/accept the use of protective glasses will be included
Exclusion criteria
Exclusion criteria: Patients who have a clearly established secondary infection at the time of admission; immunocompromised patients, those with autoimmune disease or microorganisms that compromise the immune system; who have used antibiotics in the last 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Reduction of secondary infection at the site of the bite: cellulitis and/or abscess is expected with the use of low-intensity laser therapy up to 72 hours. Secondary infection will have the following diagnostic criteria: Cellulitis will be defined by the presence of signs of local inflammation (erythema, edema, bruising and pain) associated with fever, leukocytosis, lymphangitis and/or lymphadenitis. The abscess will be characterized by individual, fluctuating lesions, presenting purulent secretion or seropurulent secretion | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: reduction of infection after 72 hours; reduction of other complications related to tissue lysis and local inflammation such as necrosis, improvement in range of motion, improvement in strength or weight bearing, local sensitivity and quality of life | — |
Countries
Brazil
Contacts
Public ContactÊndila Barbosa
Universidade do Estado do Amazonas
Outcome results
None listed