Overweight
Conditions
Interventions
Test group (n= 26): Hypocaloric meal plan (-500 kcal/day), containing a mix of Brazilian nuts (30 g cashew nut + 15 g Brazil nut), with 8 weeks duration. Control group (n= 26): Hypocaloric meal plan (
Sponsors
Universidade Federal de Viçosa
Universidade Federal de Viçosa
Eligibility
Sex/Gender
Female
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: Adult women aged 20 to 55 years; excess weight (equal or greater than 27 kg/m2), high waist circumference (equal or greater than 80 cm), and excess body fat (equal or greater than 32%) associated with at least one other cardiometabolic risk: triglycerides equal or greater than 150 mg/dL, prehypertension (equal or greater than 130 and/or 85 mmHg for systolic and diastolic arterial pressures, respectively) or fasting glycemia equal or greater than 100 mg/dL; or obesity (equal or greater than 30 kg/m2), high waist circumference (equal or greater than 80 cm), and excess body fat (equal or greater than 32%).
Exclusion criteria
Exclusion criteria: Pregnant women, nursing mothers, or women in menopause; athletes; vegans; smokers; with a history of HIV, illness or digestive, liver, kidney, cardiovascular, thyroid, cancer, inflammatory diseases and eating disorders; history of drug and / or alcohol abuse; aversion or allergy to nuts; infectious episode in the last month; use of anti-inflammatory drugs, corticosteroids, antibiotics and others that may affect energy appetite and metabolism; weight instability (5% of usual weight) in the last 3 months; usual consumption of nuts greater than 30 g/day; alcohol consumption greater than 21 units (168g) per week; dental problems that interfere with chewing; consumption of vitamin, mineral and omega 3 supplements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: The consumption of a mix containing cashew nuts and brazil nuts associated with a hypocaloric diet will reduce body weight and waist circumference by at least 5% compared to the control (hypocaloric diet free of nuts). All analyses will be performed at the end of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: The consumption of a mix containing cashew nuts and brazil nuts associated with a hypocaloric diet will increase the postprandial metabolic rate (accessed by calorimetry), by at least 5% compared to the control (hypocaloric diet free of nuts). All analyses will be performed at the end of the study.;Expected outcome 3: The consumption of a mix containing cashew nuts and brazil nuts associated with a hypocaloric diet will reduce appetite and increase satiety (evaluated by means of questionnaires of Visual Analog Scale), contributing to a reduction in habitual food intake (assessed through dietary records), compared to the control (hypocaloric diet free of nuts). All analyses will be performed at the end of the study.;Expected outcome 5: The consumption of a mix containing cashew nuts and brazil nuts associated with a hypocaloric diet will increase the gene expression of sirtuin 1 (SIRT 1), compared to the control (hypocaloric diet free of nuts). All analyses will be performed at the end of the study.;Expected outcome 4: The consumption of a mix containing cashew nuts and brazil nuts associated with a hypocaloric diet will decrease pro-inflammatory markers (assessed by plasma markers: IL-6, C-reactive protein), and increase the anti-inflammatory marker (assessed by plasma marker: IL-10), compared to the control (hypocaloric diet free of nuts). All analyses will be performed at the end of the study.;Expected outcome 6: The consumption of a mix containing cashew nuts and Brazil nuts associated with a hypocaloric diet will decrease the concentrations of cardiometabolic risk markers, such as lipidic profile, apolipoproteins, and glucose, compared to the control (hypocaloric diet free of nuts). All analyses will be performed at the end of the study.;Expected Outcome 7: The consumption of a mix containing cashew nuts and Brazil nuts associated with a hypocaloric diet will increase selenium concentrations, compared to the control. All analyzes will | — |
Countries
Brazil
Contacts
Public ContactJosefina Bressan
Universidade Federal de Viçosa
Outcome results
None listed