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Effect of the Manual Diaphragm Release Technique on Neurological Patients on Artificial Respiration

Effect of Manual Diaphragm Release Technique on Respiratory Biomechanics in Neurocritical patients on Mechanical Ventilation: Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3ngffwr
Enrollment
Unknown
Registered
2020-11-27
Start date
2021-01-25
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

disorders of nerves, roots and nerve plexuses

Interventions

The sample will be of the non-probabilistic type, due to accessibility and patients will be divided into two groups: GI,n=10 (Intervention group) in which they will receive, in addition to convention
and CG, n=10 (Control Group), where they will receive only conventional physical therapy. Anthropometric, clinical and demographic data will be collected upon admission to the ICU and fulfilling the
E02.779
E02.190.599

Sponsors

Universidade de Pernambuco
Lead Sponsor

Eligibility

Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Neurocritical patients from the Intensive Care Unit, University Hospital (HU) breathing by artificial airway (endotracheal tube) in PMV.

Exclusion criteria

Exclusion criteria: Patients with acute decline in neurological status; elevation of refractory intracranial pressure; hemodynamic instability; hypotension (mean arterial pressure less than 60mmHg); pharmacological paralysis; mechanical ventilation with positive end-expiratory pressure (PEEP) bigger then 8cmH2O, Inspired oxygen fraction (FiO2) greater than 60%; tetany; continuous renal replacement therapy; discomfort status; body mass index bigger then 30 kg / m2; previous chest surgery; chest instability; presence of chest tube; and any clinical changes for handling to perform the technique.

Design outcomes

Primary

MeasureTime frame
To evaluate mobility, contraction speed and relaxation speed using kinesiological ultrasound and presentation of parameters in centimeters, based on the observation of a variation of at least 5% in the pre and post-intervention measurements

Secondary

MeasureTime frame
secondary outcomes will be the ventilatory monitoring parameters: static and dynamic compliance, in mL / cmH2O; the maximum inspiratory pressure (PIP, in cmH2O) necessary to generate a tidal volume suitable for age (6 to 8mL per Kg of predicted weight) and respiratory work (joules / liter; from the verification of a variation of at least 5% in the measurements pre and post intervention

Countries

Brazil

Contacts

Public ContactHeitor Cavalini

Universidade de Pernambuco

heitorcavalini@gmail.com+55(11)979704553

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 2, 2026