Non-alcoholic Fatty Liver Disease
Conditions
Interventions
This is a double-blind, parallel-arm clinical trial, based on a convenience sample of random people attending the Heptatology service at the Hospital Universitário Clementino Fraga Filho who meet the
Sponsors
Universidade Federal do Rio de Janeiro
Universidade Federal do Rio de Janeiro
Eligibility
Inclusion criteria
Inclusion criteria: Patients from the Hepatology Service of the Clementino Fraga Filho University Hospital diagnosed with non-alcoholic fatty liver disease; both gender
Exclusion criteria
Exclusion criteria: Totally edentulous patients; patients with less than 10 teeth present; smoking patients; patients who have used antibiotic medication in the last six months at baseline, anti-inflammatories or medications potentially inducing gingival hyperplasia (phenytoin, nifedipine and cyclosporine) in the last three months; patients with indication of antibiotic prophylaxis for periodontal clinical approaches; patients undergoing periodontal treatment in the last six months; patients undergoing orthodontic treatment; and patients with any syndrome, except metabolic syndrome; patients who have already used medication that induces hepatic steatosis (e.g. amiodarone, tamoxifen and methotrexate); third molars, residual roots, teeth with non-carious cervical lesion, caries lesion or subgingival restoration, teeth with altered development associated with protective and/or supporting periodontal tissues, teeth involved in local pathological processes, teeth with suspected fracture, teeth with previous or current history of endodontic accident/complication, or even endoperiodontal injury, will not be considered in the periodontal evaluation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effects of periodontal treatment (dental care) in patients with liver disease after periodontal treatment and vice versa. Through periodontal probing, where the clinical level of insertion, probing depth, bleeding on probing, furcation involvement, suppuration and tooth mobility will be seen; and plaque and gingival index cards. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected. | — |
Countries
Brazil
Contacts
Public ContactMaria Cynésia de Barros
Universidade Federal do Rio de Janeiro
Outcome results
None listed