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Effect of Non-Invasive Neuromodulation in improving balance and gait of individuals with Parkinson´s disease

Effectiveness of Transcranial Direct Current Stimulation associated with Physiotherapy in improving balance and gait of individuals with Parkinson´s disease: randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3mywq86
Enrollment
Unknown
Registered
2022-08-26
Start date
2022-08-30
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson disease

Interventions

The sample will be composed of individuals with Parkinson's disease, divided into three groups that will be randomized through a random number table: real transcranial stimulation + physical therapy g
E01.370.600.250
E02.779
E02.331.750

Sponsors

Universidade Estadual de Londrina
Lead Sponsor
Universidade Estadual de Londrina
Collaborator

Eligibility

Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: Medical diagnosis of Parkinson's disease according to the criteria of the London Brain Bank (Uk Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria); age range between 50 and 85 years; not institutionalized; mini-mental score that does not characterize cognitive impairment; Hoehn&Yahr scale between 1.5 and 3.0; which accept to participate of the project and sign the consent term according to the criteria of the Ethics Committee of the Universidade Estadual de Londrina, according to the parecer 466/2912 (National Health Council)

Exclusion criteria

Exclusion criteria: Individuals who perform another therapeutic treatment beyond medication; that has change in medication during the study; or those with associated diseases, such as neurological disorders, severe heart disease, amputations, cognitive or understanding deficits. Change in the stabilization of the antiparkinsonian medication doses throughout the study

Design outcomes

Primary

MeasureTime frame
Gait is expected to improve evaluated in the gait laboratory through the following parameters: increase in step length, increase in gait speed and facilitation to overcome obstacle, that is, to overcome the obstacle without significant change in speed. The gait laboratory is composed of 7 cameras, which capture all the patient's movements in 3D. The kinematic analysis of gait will be performed by filming the patient during the following activities: walking at normal speed, walking performing simple counts and overcoming obstacles while walking.;Postural balance is expected to improve assessed before and after the intervention by assessment performed in a gait laboratory, analyzing the following parameters: decrease in displacement and in anteroposterior and mediolateral amplitude of the center of mass, which means that the patient oscillated less. Patients will be evaluated with feet parallel and with one foot positioned in front of the other, in the condition of eyes open and eyes closed.

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

Brazil

Contacts

Public ContactSuhaila Smaili Santos

Universidade Estadual de Londrina

suhaila@uel.br+55 (43) 3371-2320

Outcome results

None listed

Source: REBEC (via WHO ICTRP)