Second degree burn
Conditions
Interventions
The 20 participants will be randomly allocated into two groups of the same size. The experimental group, with 10 participants, will be submitted to irradiation with light emitting diode, 658nm wavelen
Device
E02.774
E02.594.540
Sponsors
Universidade Estadual do Piauí
Centro Universitário Uninovafapi
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: They nedd to have a seconddegree burn in the region of the arm, forearm, thorax or lower limbs; age between 18 and 60 years;to be in the hospital for second degree burn treatment in the Burn Therapy Unit; to be hemodynamically stable according to blood pressure, diuresis, heart rate and respiratory rate, axillary temperature and transcutaneous oxygen saturation.
Exclusion criteria
Exclusion criteria: Patient with blood dyscrasia with predisposition to hemorrhage; presence of gangrene, renal failure, pregnancy or photosensitivity; bacterial infection at the burn site; patient with hypotension, tachycardia, tachypnea, oliguria or cyanosis; patients with comorbidities that may interfere with the healing process, such as: diabetes mellitus, malnutrition, obesity and smoking; patients who use illicit drugs or medications that interfere with the healing process of wounds, such as: chemotherapy and antibiotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acceleration of healing. Evaluated by clinical visual inspection and recorded by photograph. Aspects to be considered: wound area, amount of exudate and appearance of the wound. ;Morphometric evaluation of the wound area by the healing index. Refers to the calculation of the area of the wound before and after the intervention, presented in percentage of healing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Biopsy before and after intervention. Histomorphometric evaluation with inflammatory cell counts, fibroblast counts and collagen proliferation area using histological sections stained with hematoxylin and eosin, Masson trichrome and picro syrius red.;Analysis of the qualitative composition of the tissue by FT Raman spectroscopy. It is expected that there will be an increase in the spectroscopic peaks relative to the amino acids, which is directly related to the protein components. Increased local protein may indicate increased collagen in the healing process. | — |
Countries
Brazil
Contacts
Public ContactDenyberg;Rauirys Santiago;Oliveira
Centro Universitário Uninovafapi;Centro Universitário Uninovafapi
Outcome results
None listed