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Prophylactic antibiotic therapy indicated in reduction mammoplasty: clarifying its role in the prevention of surgical wound infection

Effectiveness of antibiotic prophylaxis in a single dose in the infection prevention on reduction mammoplasty surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3jtgfh
Enrollment
Unknown
Registered
2016-05-28
Start date
2015-01-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mammary hipertrophy

Interventions

Cephalothin 2g intravenous administration in single dose 30 minutes before mammaplasty surgery in a experimental group of 75 patients and other 75 patients control group without the use of antibiotic
Drug

Sponsors

Hospital Agamenon Magalhaes
Lead Sponsor
Hospital Agamenon Magalhaes
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: woman, age from 18 to 70 years old, approved by the hospital medical joint comission; body mass index between 25 to 30

Exclusion criteria

Exclusion criteria: Using steroids ; have used antibiotics in the last 7 days prior to the surgery

Design outcomes

Primary

MeasureTime frame
Reduction of surgical site infection rates in the group with antibiotic prophylaxis when compared to antibiotic-free control group after follow-up for 35 days after surgery, observing the surgical wound behavior weekly and throught statistical evaluation of the data, with absolute and relative frequencies for categoric variables (surgical site infection, prophylactic antibiotic, ptosis, hypertrophy) and mean, standard deviation and median for numeric variables (weight resected, surgery time)with an error margin of 5% to define its statistical significance

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactLuiz Felipe Fernandes Vieira

Hospital Agamenon Magalhaes

luizfelipedfv@uol.com.br+5581999727161

Outcome results

None listed

Source: REBEC (via WHO ICTRP)