Prevention & control
Conditions
Interventions
The present study will be a two-period crossover randomized clinical trial (n = 20 participants)
Intervention 1) Manual brushing with neutral detergent: Brushing once a day at a fixed time for two mi
Other
E06.761.726.794
Sponsors
Pontifícia Universidade Católica do Paraná
Pontifícia Universidade Católica do Paraná
Eligibility
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 60 years of age or older; complete edentulism; use of a conventional upper complete denture in acrylic resin for at least one year
Exclusion criteria
Exclusion criteria: The wear of conventional upper fractured, repaired or relined upper dentures; being in use or having used antibiotics, antifungals or corticosteroids for a period of three months prior to the study; using denture adhesives; being a smoker; using of prostheses with excessive accumulation of calculus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expected outcome will be the reduction of biofilm formation in the upper denture of each participant after applying each one of the 2 interventions The outcome will be verified from the percentage variation of the estimated microbial load of the total dentures before and after the 2 hygiene interventions The method of verification of the outcome will be MTT (3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide) assay | — |
Secondary
| Measure | Time frame |
|---|---|
| The expected outcome will be the reduction of biofilm formation in the upper denture of each participant after applying each one of the 2 interventions The outcome will be verified from the count (CFU/total surface area of denture) of 3 microorganisms (C. albicans, Streptococcus spp, Staphylococcus spp.) present in the biofilm of the total dentures before and after the 2 ultrasonic cleaning and brushing interventions Note: CFU = colony forming units | — |
Countries
Brazil
Contacts
Public ContactAna Sponchiado
Pontifícia Universidade Católica do Paraná
Outcome results
None listed