Stroke, not specified as hemorrhagic or ischemic
Conditions
Interventions
60 chronic post-stroke subjects will be randomized into two groups: EA + TCIm (30) and control: elongation + TCIm (30). Aerobic exercise and stretching will be performed for 40 min, after 10 min of re
Other
G11.427.410.698.277
Sponsors
Universidade Federal de São Carlos - UFSCar
Universidad del Rosario
Eligibility
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: Individuals with hemiparesis who present the last episode of stroke (ischemic or hemorrhagic) for more than 6 months (chronic phase after stroke). Individuals with more than one stroke may be included as long as the insult involves the same hemisphere. Only individuals who have strokes involving the territories of the middle and anterior cerebral arteries will be included. Individuals must submit a referral, imaging tests and medical report with the diagnosis of stroke. The age range should be between 35 and 80 years. As a criterion for the implementation of the ICM protocol, all participants should present a minimum active movement of 45 ° of flexion and abduction of the shoulder, 20 ° of elbow extension, 10 ° of wrist extension, 10 ° of abduction or extension of the thumb , and 10 ° extension in at least two fingers (metacarpophalangeal and interphalangeal joints) beyond the thumb. In addition, they should show asymmetry in the use of the upper limbs with a score of ? 2.5 in the Motor Activity Log quantity scale. For the proposed activities, individuals should be able to remain in the seated posture without trunk and arms support 1 minute.
Exclusion criteria
Exclusion criteria: individuals with cognitive deficits according to the Mental State Mini Exam (score less than 13 for illiterate individuals, 18 for individuals with 1 to 7 years of study, and 26 for individuals with more than 8 years of study); individuals smokers, alcohol users, users of illicit drugs; individuals with structural abnormalities in cardiovascular systems such as hypertrophic cardiomyopathy, aortic aneurysm, left bundle branch block; and respiratory; individuals with uncorrected auditory and visual deficits; electrocardiogram (ECG) abnormalities such as ischemic changes, arrhythmias (atrial fibrillation, atrial flutter), conduction disorders, both at rest and during the clinical exercise test, to be lauded by a cardiologist. In addition, individuals with historical diseases or osteomioarticular alterations that prevent the performance of the procedures or generate pain during the activities, obese (BMI> 28 kg / m2), with diabetes and uncontrolled hypertension, comprehension aphasia, apraxia, stroke bilateral, acute or subacute ( 160 mmHg and PAdiastolic 110 mmHg) or frequency (HR max = 220-age - men or 210-age women), as well as peripheral oxygenation 15 scale (0-20)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in serum and plasma concentrations of BDNF and improvement in manual dexterity assessed by the Box and Block test, immediately and 30 days post-intervention;Increase in serum and plasma concentrations of BDNF and improvement in manual dexterity assessed by the Nine Hole Peg test, immediately and 30 days post-intervention;The most active post-stroke subjects measured by the 6-minute walk test will maintain the improvement in performance and will present a higher concentration of BDNF at 30 days post-intervention;The most active post-stroke subjects measured by activity monitors (accelerometers), will maintain the improvement in performance and will present a higher concentration of BDNF at 30 days after the end of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| The most active post-stroke subjects measured by activity monitors (accelerometers), will maintain the improvement in performance and will present a higher concentration of BDNF at 30 days after the end of treatment. | — |
Countries
Brazil
Contacts
Public ContactThiago Russo
Universidade Federal de São Carlos - UFSCar
Outcome results
None listed