azoospermia
Conditions
Interventions
Single-arm prospective cohort study evaluating pre- and post-intervention. We will recruit 30 men. The individuals will be clinically evaluated in relation to anatomical changes of urinary and / or ne
Second visit - 8 hours after taking the medication
Third visit - 12 hours after taking the medication
Fourth visit - 16 hours after taking the medication
Fifth visit - 20 hours after taking the medication
Sixth visit - 24 hours after taking the medication. In the second analysis, individuals should perform a sperm collection by masturbation according to WHO guidelines and immediately after a urine coll
D27.505.696.875.360.443
Sponsors
Faculdade de Medicina do ABC
Instituto Ideia Fértil de Saúde Reprodutiva
Eligibility
Sex/Gender
Male
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Men aged 18 to 45 years; with the ability to perform sperm collection; who accept to participate as volunteers in the research
Exclusion criteria
Exclusion criteria: History of neurological changes even if treated; history of liver disease; history of kidney disease; history of use of exogenous testosterone or anabolic or androgen; history of diabetes mellitus; history of pelvic or genital surgery; concomitant use of specific medications (ketoconazole erythromycin other alpha blockers warfarin and diclofenac); inability to collect sperm by masturbation; sperm changed according to WHO standards; negative to sign a free and informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected Outcome 1: Identify azoospermia through semen analysis in all samples.;Observed Outcome 1: Azoospermia identified in 80.7%. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes were expected | — |
Countries
Brazil
Contacts
Public ContactLeonardo Lopes
Faculdade de Medicina do ABC
Outcome results
None listed