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Treatment of multiple gingival recessions using volume-stable collagen-based gingival graft substitute impregnated with blood platelet derivative: a split-mouth randomized clinical trial

Treatment of multiple gingival recessions with volume-stable collagen matrix impregnated by platelet aggregates: a split-mouth randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3hqrvrr
Enrollment
Unknown
Registered
2021-10-20
Start date
2021-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival recession

Interventions

In a sample of 25 individuals, the surgical procedure will comprise two approaches, considering that the same individual will receive an intervention group on one side of the mouth and a control group

Sponsors

Universidade Federal de Santa Catarina
Lead Sponsor
Osteology Foundation
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients requiring root coverage for multiple gingival recessions; of both sides of the mouth; in homologous teeth; in the maxillary aesthetic zone (between teeth 15 and 25); without interproximal involvement; with a minimum of three adjacent teeth in each side of the maxilla should present marginal recession at least one of them with a recession depth equal or over 3 millimeters; patients should be equal or over18 years-old; present good oral health.

Exclusion criteria

Exclusion criteria: Uncontrolled systemic or local conditions; diabetic volunteers; pregnant women; volunteers with periodontitis; smokers; volunteers with a history of mucogingival or periodontal surgery at surgical sites; prosthetic crowns at teeth or implants in the surgical sites; gingival recessions with less than 1 mm of keratinized tissue apical to recession areas.

Design outcomes

Secondary

MeasureTime frame
Improvement of the clinical parameters keratinized tissue width, bleeding on probing, probing depth, clinical attachment level, gingival thickness, and gingival phenotype measured with a periodontal probe before surgery and six months after root coverage.;Reduction on the patient-reported outcome measures such as discomfort, pain, swelling, bleeding, and ecchymosis, evaluated by a questionnaire.

Primary

MeasureTime frame
Reduction in the recession depth measured in millimeters with clinical periodontal probe from gingival margin to cemento–enamel junction at the mid-buccal site before surgery and six months after root coverage.

Countries

Brazil

Contacts

Public ContactCesar Benfatti
cesarbenfatti@yahoo.com+55 48 9922-9961

Outcome results

None listed

Source: REBEC (via WHO ICTRP)