Pre-hypertension
Conditions
Interventions
A single group of pre-hypertensive subjects will undergo 4 experimental sessions: one with exercise (cycle ergometer, 45min, 50% of VO2peak)conducted in the morning (9am), one with exercise (cycle erg
other
F01.145.632
Sponsors
Escola de Educação Física e Esporte da Universidade de São Paulo
Laboratóio de Rins e Hormônios da Escola Paulista de Medicina da Universidade Federal de São Paulo
Laboratório de Neurobiologia do Instituto de Ciências Biomédicas da Universidade de São Paulo
Eligibility
Sex/Gender
Male
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Men Aged between 20 and 40 years Systolic blood pressure between 120-139 mmHg and/or diastolic 80-89 mmHg No diabetes Sedentary or insufficiently active (did not perform physical activity more than twice a week) Non smokers Do not take any medicine that affects the cardiovascular system
Exclusion criteria
Exclusion criteria: Body Mass Index of equal to or greater than 30kg/m2 Subjects with cardiac diseases (previous diganosis or elatered rest or exercise ECG) Individuals that are experiencing poor quality sleep (score greater than 5 at Pitsburg Sleep Quality Index) - Not having chronotype intermediary, or be morning or evening
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postexercise hypotension - evaluated by the measurement of clinic (auscultatory) and ambulatory (oscillometric) blood pressure before and after rest and aerobic exercise performed in the morning and evening. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics - evaluated by the measurement of cardiac output (rebreathing of carbon dioxide) and heart rate (ECG) before and after rest and aerobic exercise performed in the morning and evening. From such data, peripheral vascular resistance and stroke volume are going to be calculated. ;Autonomic modulation - evaluated by measuring heart rate and blood pressure variabilities (spectral analysis) performed before and after rest and aerobic exercise conducted in the morning and evening. ;Função vascular - avaliada pela medida do fluxo sanguíneo basal e de sua resposta a manobra de hiperemia reativa (pletismografia de oclusão venosa) realizada antes e após o repouso e exercício aeróbico pela manhã e ao final da tarde.;Circadian endocrine regulation - evaluated by plasma levels of norepinephrine, epinephrine, angiotensin II, and vasopressin, besides the urinary melatonin metabolite 6-sulfatoxymelathonin. | — |
Countries
Brazil
Contacts
Public ContactClaudia Forjaz
Escola de Educação Física e Esporte da Universidade de São Paulo
Outcome results
None listed