Neuromuscular Diseases
Conditions
Interventions
Group 1 or control: It will have 30 patients who will perform the maximal insufflation technique with manual resuscitation bag coupled to an inflatable edge mask with totally occluded exhalation valve
Device
E02.190.525.186
Sponsors
Escola Superior de Ciências da Saúde
Escola Superior de Ciências da Saúde
Eligibility
Age
16 Years to 80 Years
Inclusion criteria
Inclusion criteria: Diagnosis of neuromuscular disease confirmed by neurologists at the referral center for neuromuscular diseases at Brasília Support Hospital prior to screening for recruitment; age over 16 years; preserved cognition, evidenced by a score greater than or equal to 24 points in the Mini-Mental Status Exam;no barium allergies; without tracheostomy or mechanical ventilation; no diaphragmatic pacemaker - without associated respiratory disease
Exclusion criteria
Exclusion criteria: less than 16 years; pregnancy; previous kidney disease or other concomitant diseases; respiratory diseases during the study; hospitalization in intensive care units (ICUs) during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum Expiratory Pressure will be measured between the groups for a change from baseline to 3 months [ Time Frame: Changes from baseline to month 3 ], with minimal variation of 10% between the training and control groups. Maximum expiratory pressure is a measure of force generating capabilities as assessed by having subjects quickly inhale then rapidly blow out air into a handheld manometer (Micro Mouth Pressure Meter). Three trails will be performed and the highest will be used.;Maximum Inspiratory Pressure will be measured between the groups for a change from baseline to month 3 [ Time Frame: Changes from baseline to month 3 ]with minimal variation of 10% between the training and control groups Maximum inspiratory pressure is a measure of force generating capabilities as assessed by having subjects quickly inhale then rapidly blow out air into a handheld manometer (Micro Mouth Pressure Meter). Three trails will be performed and the highest will be used.;Pulmonary function to measure the forced vital capacity (FVC) between the groups for a change from baseline to month 3 [ Time Frame: Changes from baseline to month 3 ]with minimal variation of 10% between the training and control groups. Pulmonary Function testing will be performed using a micro pressure meter. The participant will perform a maximum inhalation and then slowly blow out air into the mouthpiece of the meter. The following measurement will be displayed on the meter after the exhalation is complete forced vital capacity (FVC) expressed as a percentage of predicted values.;Pulmonary function to measure the peak expiratory flow (PEF) will be measured between the groups for a change from baseline to month 3 [ Time Frame: Changes from baseline to month 3 ]with minimal variation of 10% between the training and control groups. Pulmonary Function testing will be performed using a micro pressure meter. The participant will perform a maximum inhalation and then slowly blow out air into the mouthpiece of the m | — |
Secondary
| Measure | Time frame |
|---|---|
| The Penetration-aspiration scale will be used to measure swallowing function [ Time Frame: Changes from baseline to month 3 ] with minimal variation of 10% between the training and control groups Videofluoroscopic swallowing study will be performed to measure the oropharyngeal swallowing. | — |
Countries
Brazil
Contacts
Public ContactVinicius da Silva
Universidade de Brasilia
Outcome results
None listed