Coronavirus Infections Signs and Symptoms, Digestive Protein-Energy Malnutrition
Conditions
Interventions
At the hospital admission, all COVID-19 patients included (n = 370) were analyzed descriptively regarding their age, sex, race, weight, height, body mass index (BMI), presence of previous comorbiditie
Sponsors
Faculdade de Medicina da Universidade de São Paulo
Hospital Sírio Libanês
Eligibility
Age
18 Months to 90 Years
Inclusion criteria
Inclusion criteria: 18 to 90 years old; both genders; any ethnicity; diagnosis of COVID 19 confirmed by positive PCR swab; nutritional ingestion lower than 60 percent of calorie-protein needs for 2 sequential days to be included in the intervention group
Exclusion criteria
Exclusion criteria: For general population pregnancy. For intervention group diabetes mellitus II with mandatory use of insulin; dysphagia that prevented swallowing without thickener; supplemental enteral or parenteral nutrition therapy; previous use of complete oral supplement; presence of three liquid bowel movements for two days; allergy or intolerance to some component of the oral supplement; bleeding; multiple organs and systems dysfunction, Sequential Organ Failure Assessment score higher than 11 points; Karnofsky Performance Scale lower than 50 percent, other acute illness, concomitant participation in other ongoing interventionist clinical protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant attenuation of nutritional deficits influenced by gastrointestinal symptoms by oral nutritional supplementation, assessed from the meet of energy-protein needs, from the observation of an increase of at least 25% in the pre and post-intervention measures. | — |
Secondary
| Measure | Time frame |
|---|---|
| Good adherence to oral nutritional supplementation, assessed by the frequency of acceptance of the nutritional supplement offered, based on the finding of a rejection lower than 15%. ;Moderate presence of gastrointestinal manifestations, assessed by recording at admission, based on a frequency of gastrointestinal signs and symptoms higher than 35% | — |
Countries
Brazil
Contacts
Public ContactAlfredo Mansur
Outcome results
None listed