Pediatric Intensive Care Unit, Critically ill, Respiratory insufficiency Respiration, Artificial, Protein Malnutrition
Conditions
Interventions
Three groups will be evaluated:
- Intervention group with protein 1: 25 children and adolescents admitted to Pediatric Intensive Care Unit will receive a polymeric protein module diluted in water and
Dietary supplement
Sponsors
Universidade Federal de Santa Catarina
Hospital Infantil Joana de Gusmão
Eligibility
Age
1 Months to 14 Years
Inclusion criteria
Inclusion criteria: children of both sexes; aged 1 month to 14 years 11 months and 29 days of age; hospitalized for a maximum of 72 hours; with indication of enteral nutrition with polymeric diet.
Exclusion criteria
Exclusion criteria: discharge or death in the first 48 hours; inability to initiate enteral nutrition in the first 72 hours; use of parenteral nutrition; admission for moderate to severe burn; allergy to cow's milk protein or innate error metabolism; hepatic encephalopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Higher prevalence of patients with zero or positive nitrogen balance, evaluated by evaluating urine urea at 24 hours, after 5 days of intervention, in comparison to the control group | — |
Secondary
| Measure | Time frame |
|---|---|
| Lower incidence of mortality and nosocomial infection, assessed in percentual, in the intervention groups, compared to the control group, in the end of the study. Lower length of hospital and intensive care unit stay, and lower duration in mechanical ventilation, in the intervention groups, compared to the control group, in the end of the study. In the intervention groups, protein intake by enteral nutrition, after 5 days of intervention, of 1.5 to 3 g / kg / day. Maintenance in indicators of nutritional status, assessed by body mass index z-score for age, arm circumference for age, triceps skinfold for age, after 5 days of intervention. | — |
Countries
Brazil
Contacts
Public ContactDaniela;Yara Maria Hauschild;Moreno
Universidade Federal de Santa Catarina;Universidade Federal de Santa Catarina
Outcome results
None listed