Oxidative stress
Conditions
Interventions
A total of 25 participants will use 2.5g and 25 participants will use 5g of Baccharis trimera as infusion in 150 mL of water once a day.
Other
B01.650.940.800.575.912.250.100.133
Sponsors
Universidade Regional do Noroeste do Estado do Rio Grande do Sul
Universidade Regional do Noroeste do Estado do Rio Grande do Sul
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Women will be included who accept to participate in the research through the signing of the Free and Informed Consent Form, TCLE. Adhere for three months to treatment with Baccharis trimera infusion. Perform all stages of research protocol evaluations.
Exclusion criteria
Exclusion criteria: Women will be excluded the following drug classes are in continuous use: Hormone Replacement Therapy, HRT or who have previously had this treatment; vitamin supplement, medications for HAS, DM. Women who use medicinal plants on an ongoing basis;Women with low acceptability of Baccharis trimera infusion; Women who participated in the last 6 months of research with herbs, herbal medicines and functional foods.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antioxidant effect: will be checked through levels of substances reactive to thiobarbituric acid, carbonylated proteins, reduced glutathione, the activity of superoxide dismutase and catalase enzymes. | — |
Secondary
| Measure | Time frame |
|---|---|
| The verification of pressure levels will be performed using an aneroid sphygmomanometer with stethoscope Anthropometric evaluation, through the measurement of weight, height, waist circumference and body fat percentage verification, will also be used to calculate the Body Mass Index (BMI). ;Assessment of renal function through urea and creatinine analysis Analysis of hepatic function through the enzymes glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase and gamma glutamyl transferase;Definition of the climacteric phase through the dosage of 17?-estradiol levels Lipid profile through analysis of total cholesterol, High Density Lipoprotein triglycerides Analysis of blood parameters will be performed through the blood count ;Analysis of blood parameters will be performed through the blood count Fasting glucose analysis | — |
Countries
Brazil
Contacts
Public ContactDaiana Gewehr
Universidade Regional do Noroeste do Estado do Rio Grande do Sul
Outcome results
None listed