Breast neoplasms
Conditions
Interventions
Cardiopulmonary exercise testing with medical supervision will define the cardiorespiratory fitness condition, providing peak VO2 and ventilatory thresholds. Handheld dynamometer will be used to measu
Piper questionnaire for fatigue
“body image after breast cancer” for self-image
and IMPRAF-54 for regular physical activity motivation. Blood samples will be collected to laboratory testing and immune markers analysis. Body composition will be defined through weight and height me
Behavioural
G11.427.410.698.277
E02.760.169.063.500.387.875
E05.318.308.980
C23.888.369
C23.888.144
I97.2
Sponsors
Escola de Educação Física e Esporte da Universidade de São Paulo
Fundação Faculdade de Medicina
Eligibility
Sex/Gender
Female
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: Women’s volunteers; age between 35 and 75 years; from the Instituto do Câncer do Estado de São Paulo (ICESP) rehabilitation program, offered to the patients that complete breast cancer therapy; that had finished all cancer treatments.
Exclusion criteria
Exclusion criteria: Volunteers with metastatic disease; severe lymphoedema; obesity; organic dysfunctions (renal insufficiency, cardiac insufficiency and chronic liver disease); risk factors not controlled (hypercholesterolemia, diabetes, hypertension); alterations in the exercise test that contraindicate the practice of moderate physical activity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aerobic fitness: increase of 10% in peak VO2 measured by ergospirometric test performed on treadmill.;Muscle strength: increase of 5% in maximum strength measured by handheld dynamometer.;Functional capacity: increase of 5% on the number of times of the 30-second chair stand test; reduction of 7% on the time of the up and go test.;Quality of life: increase of 6% on the QLQ-C30 and SF-36 questionnaires score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fatigue: reduction of 5% on the Piper questionnaire score.;Lymphedema: reduction of 7% on the bicipital circumference.;Daily physical activity: increase of 40% in MVPA time.;Self-image: increase of 9% on the body image after breast cancer questionnaire score.;Body composition: decrease of 5% on BMI.;Immune markers: increase of 20% to 30% on the lymphocyte activation in response to antigenic stimulation; reduction of 30% on IL-6 levels; increase of 30% on interferon-gamma levels; increase of 20% on CD4 and CD8 positive cells.;Autonomic balance: reduction of 10% in sympathetic activity measured by the LF band in spectral analysis. | — |
Countries
Brazil
Contacts
Public ContactPatricia Brum
Escola de Educação Física e Esporte da Universidade de São Paulo
Outcome results
None listed