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Study of the Effectiveness of Preoperative Gabapentin in the Control of Postoperative Pain in Patients Undergoing Inguinal Hernia under Spinal Anesthesia

Study of the Effectiveness of Preoperative Gabapentin in the Control of Postoperative Pain in Patients Undergoing Inguinal Hernia under Spinal Anesthesia

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-3fv39rm
Enrollment
Unknown
Registered
2021-08-24
Start date
2019-09-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal hernia

Interventions

Experimental group: 38 patients received 900 mg of gabapentin capsuled one hour before undergoing inguinal hernioplasty surgery. Control group: 37 patients received a placebo capsule one hour before u

Sponsors

santa casa de misericordia
Lead Sponsor
santa casa de misericordia
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Both genders; age between 18 and 60 years; Maximum BMI of 30; scheduled for inguinal hernioplasty at Hospital São José do Avaí.

Exclusion criteria

Exclusion criteria: Patients with chronic opioid use; patients with chronic pain; history of chemical dependency; or those allergic to any of the medications used in the study; cardiac respiratory renal or hepatic pathology; BMI above 30 kg /m2; relapsed hernias and inguino-scrotal hernias.

Design outcomes

Primary

MeasureTime frame
Expected outcome #1: Reduction of post-operative pain, assessed by visual analog scale. Data was collected from 4 hours after surgery to a period of 30 days.;Outcome found #1: Patients who received gabapentin had lower levels of postoperative pain compared to patients who received placebo

Secondary

MeasureTime frame
Expected outcome #2: Reduction in postoperative morphine consumption. Data were collected up to 24 hours and on the thirtieth day after inguinal hernioplasty surgery.;Outcome found #2: Patients who received gabapentin perioperatively consumed less morphine compared to the group who received placebo. Results were seen at 4 hours and 24 hours after inguinal hernioplasty surgery.

Countries

Brazil

Contacts

Public ContactGlaucio Costa
gb_costa@me.com+5502132388100

Outcome results

None listed

Source: REBEC (via WHO ICTRP)