Analgesic efficacy of codeine phosphate in combination with paracetamol after wisdom tooth extractions

Analgesic efficacy of codeine phosphate in combination with paracetamol after extractions of impacted lower third molars

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-3fryp7

Enrollment

Unknown

Registered

2020-06-22

Start date

2013-11-11

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth, Impacted

Interventions

After extraction of the impacted third molar, each patient will initially receive 500mg of paracetamol in the immediate postoperative period and this medication can be replaced by the combination of 3

Drug

Procedure/surgery

C10.597.617

Eligibility

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 50 years; both sexes; no systemic disease or locoregional changes that may affect the tissue repair process or in post-operative sensitivity.

Exclusion criteria

Exclusion criteria: Contraindications of dexamethasone, paracetamol, codeine phosphate and mepivacaine.

Design outcomes

Primary

Measure	Time frame
Evaluate the analgesic efficacy using the combination of 30mg of codeine phosphate + 500mg of paracetamol, through the extraction of impacted third molars.	—

Secondary

Measure	Time frame
To evaluate the main adverse reactions using the combination of 30mg of codeine phosphate + 500mg of paracetamol in the extraction of impacted third molars.	—

Countries

Brazil

Contacts

Public ContactMaria da Graça;Matheus Naclério-Homem;de Carvalho

Universidade de São Paulo;Universidade de São Paulo

mgracanh@usp.br;dr.matheusfurtado@yahoo.com.br(11) 30917887;3232356322

Outcome results

None listed

Source: REBEC (via WHO ICTRP)