Essential (primary) Hypertension
Conditions
Interventions
This is a two-arm randomized controlled clinical trial. Experimental group: 15 sedentary hypertensive adult men will perform physical training with body weight, three times a week, for 17 weeks. Contr
b) Aerobic capacity
c) clinical systolic (SBP) and diastolic (DBP) blood pressure
d) 24-hour SBP and DBP, during wakefulness and sleep through ambulatory blood pressure mapping (ABPM)
e) Biochemical variables: fasting blood glucose, lipid profile and plasma levels of nitric oxide, nitric oxide synthase, endothelial nitric oxide synthase and glycation end products
f) endothelial function
g) sleep quality
h) quality of life.
G11.427.410.698.277
Sponsors
Universidade Federal de São Paulo
Universidade Santa Cecília
Eligibility
Sex/Gender
Male
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria will include individuals who: are male; are hypertensive through a previously requested medical report; whose hypertension is controlled by medication; are between 30 and 50 years old; have been sedentary for at least a period of 6 months; hold medical clearance to practice physical exercise; do not present injuries that limit the partial or total practice of physical exercise; agree to be volunteers for the realization of this project; provide personal and health information; perform pre-participation assessments of the exercise program; sign the free and informed consent form (TCLE)
Exclusion criteria
Exclusion criteria: Participants who change their drug treatment during their participation in the research and who, during the 17-week training period, have a frequency below 75% will be excluded from the analyses
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a decrease in the values ??of systolic and diastolic blood pressure, evaluated both clinically through the auscultatory method and 24h, evaluated through the ambulatory blood pressure monitor (ABPM), in individuals who perform physical training with weight body weight when compared both with the values ??pre-experimental period and the control group. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find improvement in anthropometric variables, such as body mass, body mass index, perimeters and skinfolds, in individuals who perform physical training with body weight when compared both with the values ??pre-experimental period and the control group.;It is expected to find an improvement in aerobic capacity, assessed through the cardiopulmonary stress test, in individuals who perform physical training with body weight when compared both with the pre-experimental period values ??and with the control group.;It is expected to find improvement in biochemical variables (fasting blood glucose, lipid profile and plasma levels of nitric oxide, nitric oxide synthase, endothelial nitric oxide synthase and glycation end products), which will be evaluated by means of specific biochemical kits, in individuals who performed physical training with body weight when compared both with the values ??pre-experimental period and the control group.;It is expected to find improvement in endothelial function, through the evaluation of flow-mediated dilation of the brachial artery, in individuals who perform physical training with body weight when compared both with the pre-experimental period values ??and the control group.;It is expected to find improvement in sleep quality, evaluated through the Pittsburgh questionnaire, in individuals who perform physical training with body weight when compared both with the values ??pre-experimental period and the control group.;It is expected to find an improvement in the quality of life, evaluated through the specific quality of life questionnaire for hypertensive patients by Bulpitt and Fletcher, in individuals who carry out physical training with body weight when compared both with the pre-experimental period values ??and those of the group control. | — |
Countries
Brazil
Contacts
Public ContactAlessandra Medeiros
Universidade Federal de São Paulo
Outcome results
None listed