Dementia, unspecified
Conditions
Interventions
Intake of probiotic Bifidobacterium longum (at a concentration of 10 to 9) and placebo, daily, for 10 weeks. 30 elderly in the placebo group received placebo via oral (capsule with starch)
30 elderly of the treated group received a probiotic capsule Bifidobacterium longum, orally.
Biological/vaccine
G07.203.300.456.500
Sponsors
Universidade Federal do Rio Grande do Norte
Universidade Federal do Rio Grande do Norte
Eligibility
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: - To be 60 years or more; being institutionalized; obtain values between 10 and 24 in the Mini Mental State Examination (MMSE), to exclude individuals with very mild dementias and very severe dementias; be able to walk
Exclusion criteria
Exclusion criteria: -Be less than 60 years; not being institutionalized; obtain value less than 10 and greater than 24 in the Mini Mental State Examination (MMSE); not being able to walk
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease of at least 10% in the concentration of some metabolites related to chronic subclinical inflammation, variation observed in the pre and post intervention measurements, verified using the Nuclear Magnetic Resonance method and analysis using Chenomx software. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive assessment performed through the "Mini mental state examination", "Rey auditory-verbal learning test (RAVLT)", and "Wechsler Adult Intelligence Scale - Revised (WAIS-R)" have not, so far, had a significant difference between pre- and post-treatment. Analyzes are still being done. | — |
Countries
Brazil
Contacts
Public ContactKenio de Lima
Universidade Federal do Rio Grande do Norte
Outcome results
None listed