Dysgeusia
Conditions
Interventions
This is a double-blind, randomized, placebo-controlled clinical trial. The sample will consist of patients from the Cancer Hospital of Pernambuco, treated at the outpatient clinic of the Department of
n=40), through simple randomization. Randomization will be performed by a responsible statistician using specific software for this purpose, which will generate a predefined list of random allocations
however, the principal investigator will simulate the application by immediately turning the device on and off, blinding the patients. The statistician supporting the work will also be unaware of whic
Sponsors
Universidade Federal de Pernambuco
Sociedade Pernambucana de Combate ao Câncer
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with performance status 0 and 1; aged 18 to 70 years; diagnosed with head and neck cancer; radiation dose of 40 Grays or more
Exclusion criteria
Exclusion criteria: Diagnosis of anemia; uncontrolled diabetes; history of use of medications that significantly altered salivary flow or saliva composition or taste; use of centrally acting analgesics or anxiolytics and antidepressants; resection in the tongue region; tumors in the tongue and base of the tongue and floor of the mouth or nearby regions that make the application of the photobiomodulation protocol unfeasible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that patients undergoing photobiomodulation will experience an improvement in their sense of taste, assessed through objective (taste strips) and subjective (taste scales) tests | — |
Secondary
| Measure | Time frame |
|---|---|
| An improvement in patients' quality of life is expected during radiotherapy treatment, as assessed using the Oral Health Impact Profile (OHIP-14) questionnaire | — |
Countries
Brazil
Contacts
Public ContactRenata Arcoverde
Sociedade Pernambucana de Combate ao Câncer
Outcome results
None listed