Study conducted with postmenopausal women with overweight or obesity. Keywords: women, menopause, obesity, cinnamon.
Conditions
Interventions
Thirty postmenopausal women with overweight or obesity will be selected to participate in a longitudinal study divided into three phases. The volunteers will be supplemented with 2g per day of cinnamo
The volunteers of the placebo group will be directed to the consumption of 6 capsules of cellulose per day (2g). The third phase (T3), eight weeks after T2, will verify the effect of cinnamon suppleme
Dietary supplement
SP6.051.227
N01.400.900
G08.686.157.500.625
Sponsors
Universidade Federal Fluminense
Universidade Federal Fluminense
Eligibility
Sex/Gender
Female
Age
45 Years to 59 Years
Inclusion criteria
Inclusion criteria: Women with 12 months of amenorrhea; overweight or obese; age between 45 and 59 years.
Exclusion criteria
Exclusion criteria: use of anticoagulants, anti-lipidemic, antihypertensive and oral hypoglycemic agents and insulin; patients with hepatic dysfunction; hormone replacement; who has had chemotherapy; who has allergy or hypersensitivity to cinnamon.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Supplementation with 2g of cinnamon (Cinnamomum zeilannicum) for 8 weeks will reduce body weight, increase lean body mass and reduce adipose tissue; will reduce total cholesterol, LDL-C, triglyceride and glycemia in postmenopausal women. Assessment of anthropometric nutritional status will be performed before and after supplementation, by measuring body weight, height and Body Mass Index (BMI); the body composition will be determined by dual beam x-ray absorptiometry (DEXA). Bioclin brand kits will be used to evaluate total cholesterol, LDL-c, and triglycerides. To evaluate glycemia the microplates will be read, using the equipment of the brand Biotek and model Synergy H1 Hybrid Reader. Student's t-test and Variance (ANOVA) analysis will be used to compare the mean within and between groups, respectively. Statistical significance will be considered p <0.05. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactLuciana;Manuela Pereira;Dolinsky
Universidade Federal Fluminense;Universidade Federal Fluminense
Outcome results
None listed