Gastroesophageal reflux disease and obesity
Conditions
Interventions
62 patients will be recruited. Patients will be randomized in blocks of 10 and divided into two groups.
Intervention group (31 patients): Will receive nutritional intervention with low-calorie diet, t
Other
Sponsors
Universidade Federal do Rio Grande do Sul - UFRGS
Universidade Federal do Rio Grande do Sul - UFRGS
Eligibility
Age
No minimum to 99 Years
Inclusion criteria
Inclusion criteria: Both sexes; age over 18 years; BMI greater than 25m ² / kg; that are experiencing typical symptoms (heartburn or regurgitation) 1 x per week or more;presence of diagnosis, confirmed by endoscopy and treatment of GERD; voluntary agreement to participate in the study.
Exclusion criteria
Exclusion criteria: Hospitalized patients; pregnant / lactating; patients who underwent surgery of the esophagus and / or stomach; cognitive inability to understand the guidelines; chronic diseases such as cancer and diabetes mellitus;presence of hiatal hernia; refractory to drug treatment; presence of complicated GERD with esophagitis grade C or D; presence of Barrett's esophagus; patient's wish to opt for surgical treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of symptoms of gastroesophageal reflux disease. Participants answered the QS-GERD Symptoms Questionnaire of Gastroesophageal Reflux Disease (GERD-QS) in which the maximum score is 55 points. This questionnaire consists of 11 questions, 10 of them answered according to a scale of 0 to 5, with the following meanings: 0, absence of symptoms; 1, symptoms without repercussion no day-to-day patient; and so gradually ate 5 indicates que que constants symptoms interfere with daily activities of patients. Statistical analysis were considered the first and last assessment to which each patient was submitted. The comparison between groups was performed by Student's t test. To control confounding factors, Analysis of Covariance (ANCOVA) was applied. The significance level was 5% (p 0.05). | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of symptoms of gastroesophageal reflux disease. Participants answered the QS-GERD Symptoms Questionnaire of Gastroesophageal Reflux Disease (GERD-QS) in which the maximum score is 55 points. This questionnaire consists of 11 questions, 10 of them answered according to a scale of 0 to 5, with the following meanings: 0, absence of symptoms; 1, symptoms without repercussion no day-to-day patient; and so gradually ate 5 indicates que que constants symptoms interfere with daily activities of patients. Statistical analysis were considered the first and last assessment to which each patient was submitted. The comparison between groups was performed by Student's t test. To control confounding factors, Analysis of Covariance (ANCOVA) was applied. The significance level was 5% (p 0.05). | — |
Countries
Brazil
Contacts
Public ContactDaieni Fernandes
Universidade Federal do Rio Grande do Sul - UFRGS
Outcome results
None listed