Halitosis
Conditions
Interventions
The number of test subjects required for the study was determined using a standardized sample size calculation based on the number of treatment groups in the cross-over study design that would achieve
Other
Sponsors
Universidade Estadual do Rio de Janeiro
Universidade Estadual do Rio de Janeiro
Eligibility
Inclusion criteria
Inclusion criteria: They were non-smokers; with no self-reported history of systemic diseases or periodontal disease; no complaints of halitosis or xerostomia; and no self-reported regular use of medicines.
Exclusion criteria
Exclusion criteria: Without systemic diasease; no periodontal treatment in the last 24 months; without the use of antibiotics in the last 6 months; without pregnancy; without orthodontic therapy; non-smokers; no cardiac pacemaker users
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presentation of expected outcome: the hypothesis to be tested was that both strontium-containing and zinc-containing toothpastes and solutions reduce VSCs in the oral cavity when tested in a 3 h cysteine challenge model. Presentation of the method used to verify the expected outcome: Measurement with gas chromatography Presentation of the parameters (numbers, percentages, indices, etc.) used to verify if the outcome actually occurred: The number of test subjects required for the study was determined on the basis of a pilot study and using a standardized sample size calculation in the number of treatment groups in the design of the cross-over study that would achieve a statistical power of 80% at a level of significance. of 5% (SigmaPlot® statistical software, San Jose, CA, USA). This process resulted in a requirement for 24-26 study participants.;Primary Outcomes After Completion: The results of this randomized, double-blind, cross-over trial demonstrated that strontium was effective in reducing H2S levels in halitosis, as demonstrated in the morning breath model. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Norway
Contacts
Public ContactLéo Soares
Universidade Estadual do Rio de Janeiro
Outcome results
None listed