Premature Rupture of Fetal Membranes
Conditions
Interventions
Patients will be randomized into two groups: Group 1: 120 patients. Oxytocin at low doses of 2 mIU / min with an increase of 2 mIU / min every 20-30 minutes. Maximum dose 40 mIU / ml. Group 2: 120 pat
Drug
O42.9
Sponsors
Hospital de Clinicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Pregnant women admitted to the maternity of the Hospital de Clínicas de Porto Alegre (HCPA) with PROM; absence of labor; indication of labor induction; unfavorable cervix (Bishop index <4); between 34 and 41 weeks of gestation.
Exclusion criteria
Exclusion criteria: Multiple gestation; previous cesarean sections; previous transmural myomectomy; non-reassuring fetal status; more than 3 contractions in 10 minutes; placenta previa or vasa previa; umbilical cord prolapse; abnormal presentations (pelvic or transverse); active herpes infection; invasive carcinoma of the uterine cervix; having denied labor induction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this study is demonstrate that the use of misoprostol to cervical ripening, in cases of RUPREME and unfavorable cervix, decreases the induction time until the beginning of the active phase of labor, increasing the chance of vaginal delivery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will be the mean time between the start of induction and delivery, side effects of both drugs and fetal outcomes. | — |
Countries
Brazil
Contacts
Public ContactFernanda Oliveira Castilhos
Hospital de Clinicas de Porto Alegre
Outcome results
None listed