in situ carcinoma, cutaneous in situ carcinoma
Conditions
Interventions
Daylight photodynamic therapy will be performed in all patients diagnosed with Bowen 's disease (a kind of superficial skin cancer) at Hospital de Clínicas de Porto Alegre, that agree to participate,
Drug
Procedure/surgery
E02.186.500
Sponsors
Hospital de Clínicas de Porto Alegre
Hospital de Clínicas de Porto Alegre
Eligibility
Inclusion criteria
Inclusion criteria: Patients with clinical and histological diagnosis of Bowen´s disease at the Department of Dermatology of the Hospital de Clínicas de Porto Alegre.
Exclusion criteria
Exclusion criteria: Patients with allergy to medications under treatment; porphyria; pregnancy; lactation; lesions in area of difficult sun exposure; lesions with clinically-suggested invasive carcinoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complete response rate 3 months after treatment with daylight-photodynamic therapy evaluated with clinical and dermatoscopic picture by a blinded dermatologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score acessed by analog pain scale during the procedure , weekly until one month after first treatment and 3 months after treatment;Local skin symptoms acessed by symptom´s questionnaire during the procedure , weekly until one month after first treatment and 3 months after treatment;Patient satisfaction acessed by questionnaire after 3 months of treatment;Cosmetical result acessed by questionnaire after 3 months of treatment;Association between complete response rate with clinical and demographic data;Association between complete response rate with day climate and weather | — |
Countries
Brazil
Contacts
Public ContactCarla Martins
Hospital de Clínicas de Porto Alegre
Outcome results
None listed