Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Ten volunteers with a clinical diagnosis of DM2 participated in the study. All volunteers were randomly submitted (raffle with opaque envelope) to 6 sessions of photobiomodulation (PBM) in a double bl
2) PBM effective with a moderate dose of light (100 J) combined with a hypoglycemic drug (routinely used by the patients)
3) effective PBM (isolated) with high dose of light (240 J)
4) effective PBM with high dose of light (240 J) combined with hypoglycemic drug (routinely used by the patients)
5) PBM placebo (isolated) with 0 J
and 6) PBM placebo (0 J) combined with hypoglycemic drug (routinely used by the patients). The PBM was applied, bilaterally, on the quadriceps femoris, hamstrings, triceps surae, and ventral region of
2) 1 hour postprandial (pre-intervention by PBM
3) 30 minutes after PBM
4) 3 hours after PBM
5) 6 hours after PBM, 6) 12 hours after PBM and 7) 24 hours after PBM. Between each PBM session, a 1-week washout was applied. All volunteers were undergone to assessments of blood glucose and heart r
E02.774
Sponsors
Universidade do Sagrado Coração
Universidade do Sagrado Coração
Eligibility
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Volunteers of both genders were recruited; aged between 40 and 80 years; body mass index (BMI) between 20 and 39.9 km/m2, ie, eutrophic; pre-obese or moderately obese subjects (grade I); and obese (grade II). Volunteers should be clinically diagnosed as diabetic (fasting glycemia less than or equal to 126 mg / dL); and be sedentary or irregularly active according to the short version of the IPAQ.
Exclusion criteria
Exclusion criteria: Volunteers who presented cancer were excluded; or history of cancer in the region of the lower and upper limbs; infection; neurological deficits; have coagulation disorders; as well as insulin-dependent volunteers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: reduced blood glucose of at least 10 mg/dl (measured by monitoring capillary blood glucose) after treatment with phototherapy dose of 100 Joules or 240 Joules;Outcome found 1: reduced blood glucose of at least 10 mg/dl (measured by capillary blood glucose monitoring) after treatment with phototherapy (isolated) using dose of 100 Joules compared to placebo group (0 Joules). | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: changes in heart rate variability (at least 3 units) after treatment with phototherapy doses of 100 Joules or 240 Joules combined or not with hypoglycemic drug (routinely used by the patients) ;Outcome found 2: increase of at least 5 units (un) in the low-frequency component of heart rate variability for placebo treatment (0 J) combined with hypoglycemic drug (routinely used by the patients), and increase of at least 10 units in the low-frequency component for treatment with phototherapy (isolated) with dose of 100 J. | — |
Countries
Brazil
Contacts
Public ContactCleber Ferraresi
Universidade do Sagrado Coração
Outcome results
None listed