Cleft Palate
Conditions
Interventions
This is a prospective longitudinal clinical study, qualitative and quantitative, in vivo. A convenience sample will be selected from a total of 100 newborn babies, of both genders, divided into 5 grou
E02.760.731.775.500
Sponsors
Faculdade de Odontologia da Universidade Federal de Minas Gerais
Hospital da Baleia
Eligibility
Age
No minimum to 1 Months
Inclusion criteria
Inclusion criteria: Non-syndromic individuals with unilateral or bilateral cleft lip and palate; individuals born up to 3 weeks old (control and to be treated with NAM); individuals aged up to 2 years (groups not treated with NAM – pre and post surgical follow-up); male and female babies individuals with no cleft lip and palate (control group); individuals without a medical history of recurrent middle ear otitis; individuals whose parents and/or guardians agree to participate in the study and sign the TCLE; individuals whose parents or guardians are of legal age
Exclusion criteria
Exclusion criteria: Cleft individuals with other systemic diseases; participants with incomplete cleft lip and palate; individuals who have already undergone palate repair surgery; individuals using topical or systemic antibiotics or corticosteroids, individuals whose parents or guardians are minors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analyzing the maxillomandibular and nasal growth of participants with Cleft Lip and Palate, through measurements in the first month of life, pre and post surgery for babies with cleft lip and palate and at 6 months for nomotypic babies | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the proteins associated with maxillary bone remodeling of normotypic babies with Cleft Lip babies | — |
Countries
Brazil
Contacts
Public ContactJosé Dilson Júnior
Faculdade de Odontologia da Universidade Federal de Minas Gerais
Outcome results
None listed