Major Depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Right-handed; sedentary for more than three months; performing more than one month pharmacological treatment; clinical diagnosis using the criteria of the Diagnostic and Statistical Manual of Mental Disorders 4th Edition (DSM-IV).
Exclusion criteria
Exclusion criteria: Score over 18 points on the Hamilton Depression Scale; Score under 24 points in the Mini - Mental State Examination; Psychiatric comorbidities; neurodegenerative disease; severe cardiovascular disease; illiteracy; poor mobility; balance disorders; visual and / or auditory sharp.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reducing depressive symptoms at six months, verified by the Hamilton Depression Rating Scale and the Beck Depression Inventory, evidenced from the reduction of 50% in the pre and post intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of cognitive functions in six months, verified by a neuropsychological analysis, from the observation of a variation of at least 10% in the pre and post intervention measurements.;Improvement in quality of life and physical and functional capacity in six months, verified by physical evaluation, from the observation of a variation of at least 10% in the pre and post intervention measurements.;Neurophysiological improvement in six months, verified through non-invasive electroencephalographic measures, from the observation of a modification of cortical electrical pattern found between pre and post. | — |
Countries
Brazil
Contacts
Instituto de Psiquiatria - IPUB