Abdominal Obesity
Conditions
Interventions
The study sample will consist of fifty-two individuals, who will be subdivided into two stages. Stage two: The study will be randomized, cross-over, double-blind, and placebo-controlled, where volunte
Intake of a mixed high-carbohydrate meal (63% of total caloric value) with cornstarch (placebo). The meals were consumed while the patients were fasting. Participants were randomized between the group
B01.875.800.575.912.250.859.937.406.088
G07.203.300.484
Sponsors
Universidade Federal do Rio de Janeiro Campus Macaé
Universidade Federal do Rio de Janeiro Campus Macaé
Eligibility
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Stage 2: healthy individuals of both sexes aged between 18 and 40 years. Stage 3: abdominal obesity as waist circumference greater than 102 cm for men and greater than 88cm for women; low levels (less than 40 mg/dL) of serum high-density lipoprotein cholesterol - HDL; hypertriglyceridemia as 150 mg/dL or higher; blood pressure of 130/85 mmHg or higher; and deficit in glucose homeostasis as fasting plasma glucose levels 100 mg/dL or higher; of both sexes; aged between 18 and 75 years old
Exclusion criteria
Exclusion criteria: Step 2: smokers; pregnant women; breastfeeding women; people with food allergies to flours, jackfruit, and its by-products, or any other food that will be offered; people taking drugs that interfere with the vascular system. Step 3: pregnant or breastfeeding women; human immunodeficiency virus (HIV) carriers; chronic corticosteroid users; those with food allergies to flour, jackfruit, and its by-products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that the intake of jackfruit seed flour will promote an improvement in macrovascular endothelial function, as assessed by flow-mediated dilation using ultrasound, performed before and after the intervention.;It is expected that the intake of jackfruit seed flour will promote an improvement in microvascular reactivity, as assessed by near-infrared spectroscopy, carried out before and after the intervention.;It is expected that the intake of jackfruit seed flour will promote the maintenance of glucose homeostasis, assessed through glucose levels, insulin, plasma glycated hemoglobin and HOMA-IR calculation, carried out before and after the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that the intake of jackfruit seed flour will promote more satiety. | — |
Countries
Brazil
Contacts
Public ContactThiago Alvares
Universidade Federal do Rio de Janeiro Campus Macaé
Outcome results
None listed