Patients with vocal tremor
Conditions
Interventions
Intervention Group 1: Patients with vocal tremor subjected to the use of Propranolol tablets orally in increasing doses and increments of 20-80 mg per day administered twice daily with a duration of 1
drug
HP4.018.158.692
D02.033.100.624.836
Sponsors
Universidade Federal de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: presence of vocal tremor to perceptual analysis and larynx; older than 18 years, both sexes
Exclusion criteria
Exclusion criteria: presence of laryngeal spasm during laryngoscopy or auditory perceptual, presence of lesions on laryngoscopy, patients with previous treatment, contraindication to propranolol or botulinum toxin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perceptual-hearing evaluation of voice will be conducted through the scale RASAT whose main parameter is the measurement of vocal instability in a score of 0-3. The parameters of acoustic analysis will be evaluated: Fundamental frequency; Standard deviation of Fundamental Frequency; Variability of Fundamental Frequency; Jitter and shimmer; Diagram phonatory deviation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment will be conducted through patient satisfaction visual analog scale 0-100 mm, with the parameters: Overall satisfaction Improved voice Decreased tremor Swallowing problems. Which week? Breathiness. Which week? Cough. Which week? | — |
Countries
Brazil
Contacts
Public ContactBruno Moraes
Universidade Federal de São Paulo
Outcome results
None listed