Spinal cord injuries.
Conditions
Interventions
The intervention (training) consists of two protocols: blood flow restriction and functional electrostimulation.
Combined Group: The two techniques were applied to 9 individuals (right thigh + left
Other
E02.331.800
Sponsors
Universidade Federal do Paraná
Universidade Federal do Paraná
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Men volunteers with complete spinal cord injury (ASIA A) and eligible for quadriceps responsiveness.
Exclusion criteria
Exclusion criteria: Cauda equina injury; spinal shock; venous thrombosis; autonomic dysreflexia; vascular complications; pressure ulcers; osteoporosis; recent fracture; implants and femur metal pins and two consecutive absences to the training sessions as well.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1- Expected primary outcome: Chronic increases in muscle mass measurement in the combined training group are expected to be significantly higher than the measurements in the individual group. It will be verified by the ultrasound technique, during the period of 8 weeks.;1- Primary outcome found: Chronic increases in muscle mass measurements (11.7% = 2.67cm) in the combined training group significantly higher than the measurements in the individual group (non-significant values), using the ultrasound technique, during the 8-week period.;2- Expected primary outcome: It is expected to find sharp increases in the measurement of muscle mass in the combined training group, significantly higher than the measurements in the individual group. It will be checked by ultrasound technique, before exercise and 5 minutes after the first training session.;2- Primary outcome found: Acute increases in muscle mass measurements (19.7% = 2.79cm) in the combined training group are significantly higher than the values of the individual group (7.6% = 2.68cm), using the ultrasound technique, assessed before exercise and 5 minutes after the first training session.;3- Expected primary outcome: It is expected to find sharp increases in the measure of edema in the combined training group significantly higher than the measures in the individual group. It will be checked by the echo intensity technique, before exercise and 5 minutes after the first training session.;3- Primary outcome found: Acute increases in edema measurements (34.8% = 15 arbitrary units) in the combined training group are significantly higher than the values of the individual group (10.5% = 4 arbitrary units), using the echo intensity technique, assessed before the exercise and 5 minutes after the first training session.;4- Expected primary outcome: It is expected to find chronic increases in the measure of edema in the combined training group, significantly higher than the measures of the individual group. It will be verified | — |
Secondary
| Measure | Time frame |
|---|---|
| 1- Outcome secondary expected: Expected that muscle thickness will return to baseline after a detraining period (3 weeks after last trainnig session), mensured by ultrasound technique. ;1- Outcome: Muscle thickness reduced to baseline after the detraining period, by ultrasound technique. ;2- Outcome secondary expected: Expected edema will return to baseline after a detraining period (3 weeks after last trainnig session), mensured by echo intensity technique. ;2- Outcome: Edema reduced to baseline after the detraining period (3 weeks after last trainnig session), mensured by echo intensity technique. ;Information after trial completion: Muscle atrophy is one of the most evident consequences of spinal cord injuries (SCI), as a result of chronic immobility. The detrimental effects of SCI on large skeletal muscle groups may lead to secondary effects such as glucose intolerance, increased risk of metabolic syndrome and type 2 diabetes mellitus. Blood flow restriction (BFR) training has been proposed as an effective method to induce hypertrophy using low training loads, with little or no muscle damage. This study aimed to investigate the acute and chronic effects of low-intensity functional electrical stimulation (FES) combined with blood flow restriction (BFR) on muscles affected by spinal cord injury. The acute effects of one bout of FES with (FES+BFR group) and without BFR (FES group) on muscle thickness (MT) and edema formation were compared. The chronic effects on MT and edema following 8-weeks of twice weekly training with and without BFR were also compared. The FES+BFR group showed MT and edema increases compared to the FES only group (p0,05). Following 3 week of detraining, MT decreased to baseline values. No MT changes were observed in the FES group throughout the 8 weeks (p>0.05). This current study showed that 8 weeks of low-intensity FES training combined with BFR induces MT increases on the paralyzed skeletal muscles of spinal cord-injured men. The acut | — |
Countries
Brazil
Contacts
Public ContactGabriel Skiba
Universidade Federal do Paraná
Outcome results
None listed