FindTrial
Sign In

Rhizophora mangle (red mango) cream on skin wound healing

Rhizophora mangle cream on skin wound healing. randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-37hrf2
Enrollment
Unknown
Registered
2017-10-23
Start date
2017-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cutaneous wound

Interventions

The study will have 30 patients, using the upper eyelids of both eyes (60 eyelids), which will be divided into 2 groups (group A- standard and group B- treated) composed of 30 eyelids each, among whic
Drug
Procedure/surgery
E04.030
H02.403.810.788
VS2.002.001.005

Sponsors

Centro de Ciencias da Saúde da Universidade Federal de Pernambuco
Lead Sponsor
Fundação Santa Luzia
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Volunteers who will undergo plastic surgery of the upper eyelids at the Santa Luzia Foundation; Both genders; Age between 18 and 65 years; Normal preoperative blood and cardiac tests

Exclusion criteria

Exclusion criteria: Volunteer smokers; Diagnosis of infection in the eyelids; Diagnosis of cancer; Diagnosis of diabetes; Diagnosis of renal, hepatic, hematological or immune pathologies; Diagnosis of obesity; Use of immunosuppressive or corticoid medications

Design outcomes

Primary

MeasureTime frame
Improvement of the skin wound healing process of the group using Rhizophora mangle cream compared to the group using the dexpanthenol cream evaluated by morphometric and histomorphometric examination in data collected 1 week after the intervention—

Secondary

MeasureTime frame
Major retraction of the wound in the Rhizophora mangle cream group evaluated by morphometry (pachymeter for measurement) 1 week after the intervention. The degree of retraction of cutaneous wounds will be calculated from the equation formulated by Prata et al. (1988): A = pi . R . r Greater area of wound reepithelialization of the group treated with Rhizophora mangle cream evaluated by calculating the distance between the epithelia in the healing, performed through the software Pannoramic Viewer version 1.15.4 year 2014, 1 week after the intervention. Increased number of wound fibroblasts in the group using Rhizophora mangle cream evaluated by counting in a histological study 1 week after the intervention—

Countries

Brazil

Contacts

Public ContactJerrar Silva

Fundação Santa Luzia

jerrarx@hotmail.com558130320479

Outcome results

None listed

Source: REBEC (via WHO ICTRP)