Obesity
Conditions
Interventions
This is a 12-week, two-arm, double-blind, randomized controlled clinical study. Biomass Experimental Group: 42 overweight or obese men and women will receive a breakfast flavored milk drink containing
B01.875.800.575.912.250.618.937.555.500
D05.750.078.562.855.875
Sponsors
Universidade Federal de Viçosa
Universidade Federal de Viçosa
Eligibility
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Men and women; between 20 and 40 years old; body mass index between 25 and 34.9 kilograms per meter squared; body fat percentage above 30; food inhibition/disinhibition level less than or equal to 14; weight loss of less than 3 kilograms in the last 12 weeks; level of physical activity stable between irregularly active and active; who consume breakfast regularly
Exclusion criteria
Exclusion criteria: Smokers; pregnant/breastfeeding women; women who have menstrual irregularities in the last three months; elite athletes; consumption of probiotics, prebiotics or synbiotics more than 2 times/week in the month before the start of the study; changes in the level of physical activity and body weight greater than 3 kilos in the last three months; vegetarians; regular consumption of alcohol; use of supplements or medications; presence of allergy or food intolerance or aversion to the tested ingredients; gastrointestinal diseases; chronic diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to verify a 7 percent reduction in the participants' body weight, assessed using an anthropometric scale, after consuming green banana biomass for 12 weeks;It is expected to see an improvement in intestinal health, verified by genetic sequencing; reduction in fecal short-chain fatty acids concentration, verified by high-performance liquid chromatography; reduction in intestinal permeability, verified by enzyme-linked immunosorbent assays, after consuming green banana biomass for 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected a 30 percent reduction in serum concentrations of advanced glycation end products, verified by commercial immunoenzymatic assay kits, after consumption of green banana biomass for 12 weeks;It is expected a 15 percent improvement in plasma concentrations of inflammatory cytokines, assessed by flow cytometry, after consumption of green banana biomass for 12 weeks | — |
Countries
Brazil
Contacts
Public ContactNatália Bomfim
Universidade Federal de Viçosa
Outcome results
None listed