Nephrotic syndrome
Conditions
Interventions
Case group - 17 patients will take Lactobacillus plantarum, orally, in capsules containing 2.5 billion CFU, 2 x / day for a period of 12 weeks. Control group - 17 patients will receive orally capsule
Dietary supplement
SP6.051.227
Sponsors
Patrícia Marques Fortes
Hopital das Clínicas da Universidade Federal de Goiás (Centro Coordenador)
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Cases and controls: individuals 2-17 years and 11 months; of both sexes in regular outpatient follow-up for at least 1 year and that have in the last three months:24h proteinuria less than 50 mg / kg / day or 40 mg / m² of body surface area (BSA)Serum Albumin > 2.0 g / dl; total cholesterol > 170 mg / dl and / or triglyceride levels > 130 mg / dl; preserved renal function (glomerular filtration rate > 60ml / min); in corticoids (prednisone < 1mg / kg / day) and / or cyclosporin 5mg / kg / day; not in use of statins,do not have infectious processes at the time of selection; have not presented clinical or laboratory decompensated SN less than 3 months.
Exclusion criteria
Exclusion criteria: Individuals with kidney disease from stage III; pregnant women; cancer patients; acquired immunodeficiency syndrome, hypothyroidism, metabolic disease; severe cardiovascular disease; cerebrovascular diseas; symptomatic heart failure; viral or bacterial infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dyslipidemia control | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of inflammatory state | — |
Countries
Brazil
Contacts
Public ContactPatricia Fortes
Hospital das Clínicas Universidade Federal de Goiás
Outcome results
None listed