Pain Threshold
Conditions
Interventions
Will be selected 40 individuals who require bilateral extraction of upper molars. They will undergo pulpal anesthesia of the molar by blocking the posterior superior alveolar nerve and for anesthesia
Or a gel of the same composition associated with liposomes. All the Volunteers will receive both formulations at different moments. The randomization will be realized by a first researcher. A second r
Drug
Procedure/surgery
E06.892
E03.155.086.231
Sponsors
Universidade Federal de Sergipe
Faculdade de Odontologia de Piracicaba- Universidade de Campinas
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Individuals treated at the Department of Dentistry, Federal University of Sergipe ; of both genders; in the age range 18-60 Years of Age; sign an Informed Consent Form; Need of bilateral upper molars extraction
Exclusion criteria
Exclusion criteria: History of allergy or other problems arising from the use of any components of the formulations to be employed; History of methemoglobinemia; Alcoholics and toxic users; Fear of dentist; Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Liposomal lidocaine/prilocaine hydrogel proved to be better than non-lipossomal lidocaine/prilocaine hydrogel and sufficient to promote anesthesia on palatal mucosa allowing realization of the fully procedure of upper-molar extraction without any pain. | — |
Secondary
| Measure | Time frame |
|---|---|
| Longer anesthetic duration in the group with liposome-associated anesthetic gel. Evaluated by the use of needles in the palate periodically, until the patient report pain. | — |
Countries
Brazil
Contacts
Public Contactklinger Amorim
Universidade Federal de Sergipe
Outcome results
None listed