Periodontal Disease and Diabetes
Conditions
Interventions
Patients will be clinically evaluated by two previously trained periodontists. Of the sample, 10% will be examined twice for each of the clinical criteria evaluated in order to obtain the intra-examin
Procedure/surgery
Sponsors
Universidade Santo Amaro
Universidade Federal de São Paulo
Eligibility
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: The study will include patients of both sexes; who follow up at the University of Santo Amaro Dental Clinic - UNISA; aged between 40 and 75 years; with periodontal disease (moderate and advanced); periodontal disease associated or not with diabetes.
Exclusion criteria
Exclusion criteria: Exclusion criteria include toothlessness; periodontal treatment within the last six months; HIV-positive; positive-hepatitis C virus (HCV) or positive-hepatitis B (HBV); and / or other systemic disease; smoking; gingivitis or mild periodontitis; continued use of anti-inflammatory and / or immunosuppressive medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of inflammatory marker levels after 30 days from the end of periodontal treatment in the periodontal disease group when compared to the periodontal disease + diabetes group, which will be assessed through the levels of inflammatory markers (circulating microparticles and local inflammatory markers in the gingival crevicular fluid). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactCarolina França
Universidade Santo Amaro
Outcome results
None listed