Dysarthria
Conditions
Interventions
It is a prospective, longitudinal study, considered a clinical trial and “blinded by double simulation” (Medronho et al., 2009).
The TIBCO Statistica software (version 13.5.0.17) was used to calculate
grouped standard deviation of 0.66
a of 5%
95% confidence level
e, K (test power) of 90%. A sample size of 21 patients was estimated for each group.
48 consecutive patients were included, 33 male and 15 female, aged between 18 and 70 years, diagnosed with AEC3, co
Sponsors
Silvana Bommarito Monteiro
Silvana Bommarito Monteiro
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 70 years of both sexes were included; diagnosed with Spinocerebellar Ataxia Type 3; patients who had not previously undergone speech therapy; with complaints related to voice or swallowing or with associated voice and swallowing complaints
Exclusion criteria
Exclusion criteria: Patients who did not present an exclusive neurological diagnosis of Type 3 Spinocerebellar Ataxia were excluded; who had previously undergone speech therapy; patients with cognitive decline or associated serious or decompensated psychiatric disorders; non-collaborative patients or those with a low level of education; illiterate or with incomplete elementary education that would make it impossible to apply the questionnaires and understand the guidelines; with the presence of marked craniofacial or upper airway anatomical changes; grade III nasal septum deviation and grade III and IV palatine tonsils
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effects of a speech therapy rehabilitation program in the treatment of patients with SCA3 compared to patients who did not receive speech therapy treatment regarding the parameters: Speech and Voice, being assessed by the Mayo Clinic protocol and acoustic evaluation of the voice. It is expected to find a significant improvement above 50% for the group that underwent speech therapy regarding the parameters of loudness, pitch, resonance, vocal quality, prosody, articulation, speech intelligibility, breathing, and improvement in the fluency speed of the speech. speaks. ; Deglutition, being assessed by swallowing videoedoscopy and by the Eating Assessment Tool -10 (EAT-10) protocol, it is expected to find a 55% improvement in the duration of oral transit, laryngeal elevation, cough reflex, decreased residue in the upper esophageal sphincter, reduced food in the oropharynx and decreased penetrations and / or bronchospasms, mainly in liquid and solid consistencies, with a decreased risk of the degree of dysphagia.;Sleep, being assessed by polysomnography and Epworth's sleepiness scale; it is expected to find a 60% improvement in daytime sleepiness and sleep parameters such as a reduction in the sleep apnea hypopnea index, in the rate of awakenings, in addition to an improvement in oxyhemoglobin saturation and adequacy of the percentage of REM sleep stages and NOT REM;Quality of life, being verified by the protocols Health Organization Quality of Life Assessment (WHOQoL Bref), by the Quality of Life in Swallowing Disorders - (Quality of Life in Dysphagia - (SWAL-QoL) and the protocol Living with Dysarthria (VcD) and a significant improvement of 70% in the experimental group is expected in terms of the reduction of the degree of dysarthria, improvement in swallowing symptoms and, consequently, improvement in the parameters of quality of life, mainly in the psychological, physical and social aspects.;Orofacial motricity using the AMIOFE-E protocol (Myofuncti | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactGiovana Lucia Monteiro
Outcome results
None listed