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Evaluation of the efficiency of 2% Alcoholic Chlorhexidine solution versus 2% Degerming Chlorhexidine solutions associated with 0.5% Alcoholic Chlorhexidine in reducing Infections of tunneled catheters for hemodialysis: an intervention study in time series

Assessment of the effectiveness of using Chlorhexidine 2% Alcohol versus 2% Degerming Chlorhexidine + 0.5% Allcoholic Chlorhexidine in reducing Infections related to tunneled catheters for hemodialysis: a time series intervention study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-34t4kwg
Enrollment
Unknown
Registered
2025-01-31
Start date
2023-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease, stage 5

Interventions

This is a prospective intervention study in time series with a total of 242 patients. Control group (historical series): 121 patients with long-term central venous catheter (CVC) dialyzed from January
2. Clean your hands with water and antiseptic soap (minimum 30 seconds) or alcohol gel (minimum 15 seconds)
3. Put on a surgical mask and safety glasses
4. Gather the materials on the tray or cart and take them to the patient
5. Clean your hands with water and antiseptic soap (minimum 30 seconds) or alcohol gel (minimum 15 seconds)
6. Put on gloves (procedure gloves if using the dressing kit, or sterile gloves if not using the dressing kit)
7. Clean the catheter exit hole with gauze soaked in 0.9% SF using circular movements from the inside out (clean as many times as necessary)
8. Clean the catheter exit hole with gauze soaked in 2% alcoholic chlorhexidine using circular movements from the inside out (clean as
C01.195

Sponsors

Faculdade de Medicina de Botucatu
Lead Sponsor
Faculdade de Medicina de Botucatu
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients on hemodialysis using a long-term Central Venous Catheter (CVC) dialyzed at the Dialysis Unit of the Hospital das Clínicas of the Faculdade de Medicina de Botucatu (HCFMB) from January 2023 to January 2026; over 18 years old; both sexes

Exclusion criteria

Exclusion criteria: Pregnant patients; those under 18 years of age

Design outcomes

Primary

MeasureTime frame
Evaluate the reduction in infection rates related to long-term central venous catheters, including catheter ostium infection (OSI), bloodstream infection (BSI) and tunnel infection (TI)

Secondary

MeasureTime frame
Assess hospitalization and death rates resulting from infection

Countries

Brazil

Contacts

Public ContactViviane Gonçalves

Faculdade de Medicina de Botucatu

viviane_pollo@yahoo.com.br+55(14)3880-1609

Outcome results

None listed

Source: REBEC (via WHO ICTRP)