Postoperative myocardial revascularization.
Conditions
Interventions
Patients evaluated in the preoperative period (clinical and physiotherapy assessment) of coronary artery bypass grafting surgery are randomly assigned to one of the two parallel study groups. The rand
Other
Sponsors
Universidade Federal de São Carlos
Irmandade da Santa Casa de Misericórdia de Araraquara
Eligibility
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Volunteers with clinical diagnosis of coronary artery disease by coronary angiography and absence of acute or chronic lung disease, undergoing elective coronary artery bypass grafting surgery with cardiopulmonary bypass, median sternotomy incision type and interposition of saphenous vein graft, or internal mammary artery or radial.
Exclusion criteria
Exclusion criteria: Not perform the surgical procedure according to the technique already specified, reoperations and / or associated procedures like approach valvular or carotid endarterectomy, present malignant ventricular arrhythmias, complexes ventricular premature beats, supraventricular tachycardia or sinus greater than 120 beats per minute, atrioventricular block of 2nd or 3rd degree, signs of low cardiac output or ventricular failure, hypotension, heart failure and recent myocardial infarction (less than 6 months), present chronic obstructive pulmonary disease, diabetes mellitus with documented diabetic neuropathy and/or presence of disease in the kidneys and liver, users of heart pacemaker, general impairment, weakness, fever, and associated neurological sequelae and difficulty understanding and/or adherence to study procedures.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Higher limit of exercise tolerance (around 20% higher), lower values ??of dyspnea (around 50%, as assessed by the modified Borg scale CR-10) and better oxygen saturation (measured by pulse oximetry) at end of exercise (around 3%) for the CPAP group. Expected outcomes during exercise in the others days of postoperative period (3o PO, for example). | — |
Primary
| Measure | Time frame |
|---|---|
| Higher values of parasympathetic autonomic modulation (reflected by heart rate variability indices (rMSSD, pNN50, AF, among others), a noninvasive tool of cardiac autonomic nervous system evaluation); peripheral oxygen saturation (evaluted by pulse oximeter, around 3% higher); breathing pattern (measured by respiratory inductive plethysmography and evaluated by indices of pulmonary time and volumes and thoracoabdominal coordination, with better values around 20-30%),and exercise tolerance (around 20% higher) for the CPAP group. Expected outcomes during exercise/rest condition in the discharge day (around fifth postoperative day). | — |
Countries
Brazil
Contacts
Public ContactCamila Falasco Pantoni
Universidade Federal de São Carlos
Outcome results
None listed