Post-Acute COVID-19 Syndrome
Conditions
Interventions
This is a controlled and randomized clinical trial, in which 2 groups of post-COVID-19 elderly people will be evaluated (EENMCI Group: combined exercise associated with the EENMCI protocol
Control Group: combined exercise without EENMCI intervention). Assessments before the protocol will include submaximal exercise testing using the 6-minute walk test (6MWT) and sit-to-stand test (SST),
hip adduction and abduction using shin pads and squats)
and upper limb (elbow and shoulder extension and flexion
shoulder adduction and abduction) using dumbbells, starting with 1 set of 10 repetitions at 60% of 1RM in the first week and increasing to 3 sets of 10 repetitions until the 5th week. In the EENMCI gr
E02.331.800
Sponsors
Universidade Federal de São Carlos
Universidade Federal de São Carlos
Eligibility
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Elderly people of both sexes; aged over 60 years; positive diagnosis for COVID 19 according to the test at least 2 months before being included in the exercise protocol; classified with Post COVID 19 Functional Status Scale greater than 2; volunteers who tested positive for COVID 19 and were isolated at home; as per WHO guidance; elderly people who required hospitalization due to COVID 19 after 30 days of hospital discharge as previously recommended and who present post COVID 19 syndrome; patients with persistent symptoms of fatigue and dyspnea within 1 to 3 months after confirmed diagnosis of COVID 19
Exclusion criteria
Exclusion criteria: Volunteers with orthopedic or neurological impairments that prevent participation in a physical exercise program; myocardial infarction; within six months of the beginning of the study; implanted pacemaker or any metallic synthesis; history of heart disease; unstable angina; arterial hypertension controlled; uncontrolled or insulin dependent diabetes mellitus and participation in a regular physical exercise program at the beginning of the study; hospital admission less than 72 hours ago; volunteers will also be excluded if they present hypersensitivity to electrical stimulation; chronic obstructive pulmonary disease;heart failure; asthma; previous tuberculosis; bronchitis; lung cancer; a condition that may compromise the performance of functional tests, documented diabetic neuropathy; cognitive deficit; difficulty understanding or adherence to study procedures; declared users of illicit drugs; pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distance covered (meters) in the 6-minute walk test (6MWT) after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Variable square root of the mean of the square of the differences between successive iR-R (RMSSD, ms) which reflects parasympathetic modulation in the time domain and frequency domain variables, high frequency (AF, ms) that reflects parasympathetic modulation and low frequency (BF, ms) reflects parasympathetic modulation sympathetic response through heart rate variability (HRV) during the supine position and MASR after intervention.;Basal arterial diameter, FMD (mm), FMD (%), basal flow, peak flow and shear stress assessed through flow-mediated dilation of the brachial artery after intervention.;Number of cycles in the sit-stand test (SST) after intervention. | — |
Countries
Brazil
Contacts
Public ContactAudrey Silva
Universidade Federal de São Carlos
Outcome results
None listed