Parkinson's Disease, Diseases of the nervous system, Cognition, Gait, Posture,Depression, Motor Disorders, Motor Activity, Dance Therapy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients between stages 1 to 3 of the Hoehn & Yahr scale; in regular use of specific medication for Parkinson's disease.
Exclusion criteria
Exclusion criteria: Cognitive deficits that could affect the understanding of the evaluation protocol and tasks proposed in the intervention groups; auditive and visual problems not corrected; other neurological diseases and musculoskeletal problems that affect the participation in the proposed intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Benefits on cognitive aspects and gait after the intervention and maintenance of these benefits after a period without intervention (follow up) are expected as outcome. Specifically, the following primary outcomes are expected: improvements on executive function (assessed by the Wisconsin Card Test and Clox 2), memory (assessed the by Wechsler Memory Scale - revised - sub tests Logical memory I and II and Verbal Paired Associates, Wechsler Adult Intelligence Scale - revised - sub test digit spam) and attention (assessed by the Wechsler Adult Intelligence Scale - revised - symbol search). In relation to gait aspects, we expect that patients will better use the auditory rhythmic cue after the intervention protocol. A decrease in synchronization error between step and cue (average and variability of the temporal difference between metronome beep and heel strike); and an increase in gait velocity and decrease in variability of spatial temporal parameters of gait will be used to verify this outcome. In dual task condition, we expected that the dual-task promote a smaller cost to the gait of patients, especially in relation to step length and velocity and variability of spatial temporal parameters of gait with dual task. For both auditory rhythmic cue and dual task we expect that benefits will be kept after a period without intervention (follow up). Gait assessment is performed through a carpet with pressure sensors (GAITRite) in 5 conditions: free walking, walking with auditory rhythmic cue (metronome) standardized in according to the cadence of the patient, walking with auditory rhythmic cue 20% less than the cadence of the patient, walking with auditory rhythmic cue 20% more than the cadence of the patient and walking with a cognitive dual task. For both, cognitive and gait variables, specific statistics test will be used (considering data distribution) and a significant difference of p<0.05 will be adopt for all tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| Due the ability of dance promote an increase in motor, cognitive and sensory demands, other general benefits are expected for patients with Parkinson's disease. Thus, the secondary outcomes of this study include: postural control of the patients (especially, area, mean frequency and root mean square of center of pressure), assessed through a force plate with data recorded in a sampling rate of 200 Hz (3 trials of 30 seconds each in 2 experimental conditions - with and without cognitive dual task); disease severity assessed by the Hoehn & Yahr scale and Unified Parkinson’s Disease Rating Scale; global cognitive function assessed through the Mini–Mental State Examination; Constructive/Visuospatial ability assessed through the Clock Drawing Executive Test - II (Clox II); Quality of life assessed through the Parkinson's disease Questionnaire – 39 (PDQ-39); Anxiety and Depression assessed through the Hospital Anxiety and Depression Scale; Stress assessed by the Lipp Inventory of Stress Symptoms for Adults (LISS); Coordination of Upper Limbs assessed through the Annett Pegboard; Strength of Upper Limbs assessed through the muscular strength/endurance test of upper limbs – dumbbells of 1.814 Kg for women and 3.628 Kg for men are used in this test; Strength of Lower Limbs assessed through the sit-to-stand test (30 seconds); General aerobic capacity/endurance and walking ability assessed through the 6-minute walk test; Functional Balance assessed through the Berg Balance Scale; Functional Mobility assessed through the Timed up and Go Test (with and without dual task - countdown); Physical Activity Level assessed by the Baecke Physical Activity Questionnaire - modified for older adults; Fear of falls assessed through the Fall Efficacy Scale - International. For all assessments specific statistics test will be used (considering data distribution) and a significant difference of p<0.05 will be adopt for all tests. | — |
Countries
Brazil
Contacts
Universidade Estadual Paulista